Synthesis, Optimization, and Evaluation of Glycosylated Naphthalimide Derivatives as Efficient and Selective Insect β- N-Acetylhexosaminidase OfHex1 Inhibitors.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.9b02281
Abstract: Insect chitinolytic β- N-acetylhexosaminidase OfHex1, from the agricultural pest Ostrinia furnacalis (Guenée), is considered as a potential target for green pesticide design. In this study, rational molecular design and optimization led to the synthesis of… read more here.
Keywords: evaluation glycosylated; optimization evaluation; synthesis optimization; acetylhexosaminidase ofhex1 ... See more keywords
Characterization of a β-N-acetylhexosaminidase with transglycosylation activity from Metarhizium sp. A34.
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DOI: 10.1111/1750-3841.16113
Abstract: In applications of chitin, one of the most abundant resources on earth, human milk oligosaccharides with many health functions were synthesized by transglycosylation of β-N-acetylhexosaminidase. Synthesis of new transfer products can be expected by other… read more here.
Keywords: metarhizium a34; transglycosylation; transglycosylation activity; acetylhexosaminidase ... See more keywords
Mutation Hotspot for Changing the Substrate Specificity of β-N-Acetylhexosaminidase: A Library of GlcNAcases
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DOI: 10.3390/ijms232012456
Abstract: β-N-Acetylhexosaminidase from Talaromyces flavus (TfHex; EC 3.2.1.52) is an exo-glycosidase with dual activity for cleaving N-acetylglucosamine (GlcNAc) and N-acetylgalactosamine (GalNAc) units from carbohydrates. By targeting a mutation hotspot of the active site residue Glu332, we… read more here.
Keywords: mutation hotspot; acetylhexosaminidase; substrate specificity; specificity ... See more keywords