Acetylshikonin from Zicao ameliorates renal dysfunction and fibrosis in diabetic mice by inhibiting TGF-β1/Smad pathway
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DOI: 10.1007/s13577-017-0192-8
Abstract: Diabetic nephropathy (DN) is the major cause of end-stage renal disease in diabetic patients. Zicao, a well-known Chinese traditional medicine, has attracted much attention due to its beneficial effects in various medical fields. In this… read more here.
Keywords: acetylshikonin; diabetic mice; renal dysfunction; fibrosis diabetic ... See more keywords
Acetylshikonin, A Novel CYP2J2 Inhibitor, Induces Apoptosis in RCC Cells via FOXO3 Activation and ROS Elevation
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DOI: 10.1155/2022/9139338
Abstract: Acetylshikonin is a shikonin derivative originated from Lithospermum erythrorhizon roots that exhibits various biological activities, including granulation tissue formation, promotion of inflammatory effects, and inhibition of angiogenesis. The anticancer effect of acetylshikonin was also investigated… read more here.
Keywords: cyp2j2; activation; inhibitor; cell ... See more keywords