NAA10 p.(N101K) disrupts N-terminal acetyltransferase complex NatA and is associated with developmental delay and hemihypertrophy
Sign Up to like & getrecommendations! Published in 2020 at "European Journal of Human Genetics"
DOI: 10.1038/s41431-020-00728-2
Abstract: Nearly half of all human proteins are acetylated at their N-termini by the NatA N-terminal acetyltransferase complex. NAA10 is evolutionarily conserved as the catalytic subunit of NatA in complex with NAA15, but may also have… read more here.
Keywords: developmental delay; acetyltransferase complex; terminal acetyltransferase; naa10 n101k ... See more keywords
Structure of the NuA4 histone acetyltransferase complex
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2214313119
Abstract: Significance The structure of NuA4, one of two major histone acetyltransferases of Saccharomyces cerevisiae, is reported at 3.8 Å resolution. Six polypeptide chains of the complex, comprising about half the total mass, could be traced.… read more here.
Keywords: structure; histone acetyltransferase; nua4 histone; acetyltransferase complex ... See more keywords
The MOZ-BRPF1 acetyltransferase complex in epigenetic crosstalk linked to gene regulation, development, and human diseases
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2022.1115903
Abstract: Acetylation of lysine residues on histone tails is an important post-translational modification (PTM) that regulates chromatin dynamics to allow gene transcription as well as DNA replication and repair. Histone acetyltransferases (HATs) are often found in… read more here.
Keywords: acetyltransferase; epigenetic crosstalk; acetyltransferase complex; moz brpf1 ... See more keywords
The Verticillium dahliae Spt-Ada-Gcn5 Acetyltransferase Complex Subunit Ada1 Is Essential for Conidia and Microsclerotia Production and Contributes to Virulence
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2022.852571
Abstract: Verticillium dahliae is a destructive soil-borne pathogen of many economically important dicots. The genetics of pathogenesis in V. dahliae has been extensively studied. Spt-Ada-Gcn5 acetyltransferase complex (SAGA) is an ATP-independent multifunctional chromatin remodeling complex that… read more here.
Keywords: dahliae; gcn5 acetyltransferase; verticillium dahliae; spt ada ... See more keywords