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Published in 2019 at "Fitoterapia"
DOI: 10.1016/j.fitote.2019.104464
Abstract: Coptis chinensis is a widely used traditional Chinese herbal medicine. In this work, 6 new alkaloids (coptisine A-F, 1-6) and 26 known alkaloids (7-32) were isolated from the chloroform extract of the rhizomes of C.…
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Keywords:
inhibitory alkaloids;
ache inhibitory;
coptis chinensis;
alkaloids coptis ... See more keywords
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Published in 2019 at "Natural Product Research"
DOI: 10.1080/14786419.2019.1598989
Abstract: Abstract Acetylcholinesterase (AChE) inhibitors remain the class of drugs used for the treatment of Alzheimer disease (AD). For the aim of discovering new sources of potent AChE inhibitors, a combined AChE-inhibitory activity together with alkaloid…
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Keywords:
ache inhibitors;
profiling acetylcholinesterase;
silico studies;
acetylcholinesterase inhibitory ... See more keywords
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Published in 2022 at "Foods"
DOI: 10.3390/foods11152268
Abstract: In this study, the fermentation of Artemisia capillaris by probiotic Leuconostoc mesenteroides MKJW (MKJW) was optimized to increase the acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE) inhibitory and antioxidant activities using the response surface method (RSM). The…
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Keywords:
buche inhibitory;
artemisia capillaris;
inhibitory;
fermentation ... See more keywords
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Published in 2023 at "Molecules"
DOI: 10.3390/molecules28083357
Abstract: Alzheimer’s disease (AD) is a neurodegenerative disease characterized by progressive memory loss and cognitive impairment due in part to a severe loss of cholinergic neurons in specific brain areas. AD is the most common type…
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Keywords:
lupinine derivatives;
ache;
inhibition acetylcholinesterase;
acetylcholinesterase novel ... See more keywords