Can Cysteine Protease Cross-class Inhibitors Achieve Selectivity?
Sign Up to like & getrecommendations! Published in 2019 at "Journal of medicinal chemistry"
DOI: 10.1021/acs.jmedchem.9b00683
Abstract: Cysteine proteases are important targets for the discovery of novel therapeutics for many human diseases. From parasitic diseases to cancer, cysteine proteases follow a common mechanism, the formation of an encounter complex with subsequent nucleophilic… read more here.
Keywords: cysteine; cysteine protease; cross; achieve selectivity ... See more keywords