AChR antibodies show a complex interaction with human skeletal muscle cells in a transcriptomic study
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-68185-x
Abstract: Acetylcholine receptor (AChR) antibodies are the most important pathogenic marker in patients with myasthenia gravis (MG). The antibodies bind to AChRs on the postsynaptic membrane, and this leads to receptor degradation, destruction, or functional blocking… read more here.
Keywords: skeletal muscle; achr antibodies; muscle cells; human skeletal ... See more keywords
Isaacs syndrome associated with GABAB and AChR antibodies in sarcomatoid carcinoma
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DOI: 10.1212/wnl.0000000000006286
Abstract: Isaacs syndrome is an acquired peripheral nerve hyperexcitability syndrome characterized by twitching, painful cramps, stiffness, delayed muscle relaxation, and sweating.1 Needle EMG findings include continuous single motor unit discharges occurring as doublets, triplets, and multiplet… read more here.
Keywords: sarcomatoid carcinoma; achr antibodies; carcinoma; isaacs syndrome ... See more keywords