Chemical and metabolic analysis of Achyranthes bidentate saponins with intestinal microflora‐mediated biotransformation by ultra‐performance liquid chromatography‐quadrupole time‐of‐flight mass spectrometry coupled with metabolism platform
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Pharmaceutical and Biomedical Analysis"
DOI: 10.1016/j.jpba.2019.03.041
Abstract: Graphical abstract Figure. No Caption available. HighlightsA total of 40 triterpene saponins were identified from the Achyranthes bidentate (AB) extract.39 metabolites of AB triterpene saponins transformed by intestinal microflora in vitro were characterized.Deglycosylation, glycosylation, oxidation… read more here.
Keywords: metabolism; analysis; achyranthes bidentate; intestinal microflora ... See more keywords
Anti-inflammatory Activity of a Polypeptide Fraction From Achyranthes bidentate in Amyloid β Oligomers Induced Model of Alzheimer’s Disease
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2021.716177
Abstract: Neuroinflammation plays a crucial role in neurodegenerative diseases such as Alzheimer’s disease (AD) and Parkinson’s disease (PD), and anti-inflammation has been considered as a potential therapeutic strategy. Achyranthes bidentate polypeptide fraction k (ABPPk) was shown… read more here.
Keywords: microglia; alzheimer disease; achyranthes bidentate; polypeptide fraction ... See more keywords