Titrating bacterial growth and chemical biosynthesis for efficient N-acetylglucosamine and N-acetylneuraminic acid bioproduction
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DOI: 10.1038/s41467-020-18960-1
Abstract: Metabolic engineering facilitates chemical biosynthesis by rewiring cellular resources to produce target compounds. However, an imbalance between cell growth and bioproduction often reduces production efficiency. Genetic code expansion (GCE)-based orthogonal translation systems incorporating non-canonical amino… read more here.
Keywords: biosynthesis; acid bioproduction; acetylneuraminic acid; growth ... See more keywords