Identification of a malonyl CoA‐acyl carrier protein transacylase and its regulatory role in fatty acid biosynthesis in oleaginous microalga Nannochloropsis oceanica
Sign Up to like & getrecommendations! Published in 2017 at "Biotechnology and Applied Biochemistry"
DOI: 10.1002/bab.1531
Abstract: Oleaginous microalgae hold great promises for biofuel production. However, commercialization of microalgal biofuels remains impracticable due to the lack of suitable industrial strains with high growth rate and lipid productivity. Engineering of metabolic pathways is… read more here.
Keywords: acid biosynthesis; fatty acid; acyl carrier; malonyl coa ... See more keywords
Genetic engineering of the branched-chain fatty acid biosynthesis pathway to enhance the surfactin production from Bacillus subtilis.
Sign Up to like & getrecommendations! Published in 2022 at "Biotechnology and applied biochemistry"
DOI: 10.1002/bab.2346
Abstract: The surfactin composed of a β-hydroxy fatty acid chain and a peptide ring has drawn considerable attention due to potential applications in biomedicine, bioremediation and petroleum industries. However, the low yield of surfactin from wild… read more here.
Keywords: surfactin production; acid biosynthesis; fatty acid; surfactin ... See more keywords
The effect of AINTEGUMENTA-LIKE 7 over-expression on seed fatty acid biosynthesis, storage oil accumulation and the transcriptome in Arabidopsis thaliana.
Sign Up to like & getrecommendations! Published in 2021 at "Plant cell reports"
DOI: 10.1007/s00299-021-02715-3
Abstract: KEY MESSAGE AIL7 over-expression modulates fatty acid biosynthesis and triacylglycerol accumulation in Arabidopsis developing seeds through the transcriptional regulation of associated genes. Seed fatty acids (FAs) and triacylglycerol (TAG) contribute to many functions in plants,… read more here.
Keywords: seed; accumulation; acid biosynthesis; fatty acid ... See more keywords
Genetic Variation for Seed Oil Biosynthesis in Soybean
Sign Up to like & getrecommendations! Published in 2021 at "Plant Molecular Biology Reporter"
DOI: 10.1007/s11105-020-01276-1
Abstract: Soybean is an important oilseed crop which supplies both industrial processes and animal feed as well as having a number of food uses. The high yields of oil from soybean seed, along with large planting… read more here.
Keywords: acid biosynthesis; oil; fatty acid; soybean ... See more keywords
PKD2 deficiency suppresses amino acid biosynthesis in ADPKD by impairing the PERK-TBL2-eIF2ɑ-ATF4 pathway.
Sign Up to like & getrecommendations! Published in 2021 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2021.05.012
Abstract: Metabolic reprogramming is emerging as a key pathological contributor to the progression of autosomal dominant polycystic kidney disease (ADPKD), but the molecular mechanisms underlying dysregulated cellular metabolism remain elusive. Here we report that amino acid… read more here.
Keywords: eif2 atf4; eif2; amino acid; acid biosynthesis ... See more keywords
Engineering a colanic acid biosynthesis pathway in E. coli for manufacturing 2’-fucosyllactose
Sign Up to like & getrecommendations! Published in 2020 at "Process Biochemistry"
DOI: 10.1016/j.procbio.2020.04.017
Abstract: Abstract Human milk oligosaccharides (HMOs) are beneficial for infants’ health and growth. As one of the most abundant oligosaccharides in human milk, 2′-fucosyllactose (2′-FL) has been approved to supplement in infant formula. Microbial synthesis of… read more here.
Keywords: acid biosynthesis; pathway; colanic acid; engineering colanic ... See more keywords
Genome Mining Reveals the Phosphonoalamide Natural Products and a New Route in Phosphonic Acid Biosynthesis.
Sign Up to like & getrecommendations! Published in 2020 at "ACS chemical biology"
DOI: 10.1021/acschembio.0c00256
Abstract: Phosphonic acid natural products have potent inhibitory activities that have led to their application as antibiotics. Recent studies uncovered large collections of gene clusters encoding for unknown phosphonic acids across microbial genomes. However, our limited… read more here.
Keywords: natural products; acid biosynthesis; phosphonic acid; genome mining ... See more keywords
Characterization of Dichloroisoeverninic Acid Biosynthesis and Chemoenzymatic Synthesis of New Orthosomycins.
Sign Up to like & getrecommendations! Published in 2024 at "ACS chemical biology"
DOI: 10.1021/acschembio.3c00693
Abstract: The orthosomycins are highly modified oligosaccharide natural products with a broad spectrum and potent antimicrobial activities. These include everninomicins and avilamycins, which inhibit protein translation by binding a unique site on the bacterial ribosome. Notably,… read more here.
Keywords: acid biosynthesis; dichloroisoeverninic acid; biosynthesis chemoenzymatic; characterization dichloroisoeverninic ... See more keywords
Real-time monitoring of the sialic acid biosynthesis pathway by NMR
Sign Up to like & getrecommendations! Published in 2023 at "Chemical Science"
DOI: 10.1039/d2sc06986e
Abstract: Sialic acids are part of the outermost component of the glycocalyx of all vertebrates; as such, they are fundamental markers in physiological and pathological processes. In this study, we introduce a real-time assay to monitor… read more here.
Keywords: biosynthesis; acid biosynthesis; time monitoring; real time ... See more keywords
Pulcherriminic acid biosynthesis and transport: insights from a heterologous system in Saccharomyces cerevisiae
Sign Up to like & getrecommendations! Published in 2025 at "FEMS Yeast Research"
DOI: 10.1093/femsyr/foaf039
Abstract: Pulcherriminic acid is an iron chelator produced by some Kluyveromyces and Metschnikowia yeasts. Its biosynthesis is encoded by the four–gene PUL cluster, where PUL1 and PUL2 are the biosynthetic enzymes, PUL3 mediates the uptake of… read more here.
Keywords: system; pulcherriminic acid; acid biosynthesis; acid ... See more keywords
Jasmonic acid regulates the biosynthesis of medicinal metabolites via the JAZ9-MYB76 complex in Salvia miltiorrhiza.
Sign Up to like & getrecommendations! Published in 2023 at "Horticulture research"
DOI: 10.1093/hr/uhad004
Abstract: Jasmonic acid (JA) signaling pathway plays an important role in tanshinone and phenolic acid biosynthesis in Salvia miltiorrhiza. However, the specific regulatory mechanism remains largely unclear. Previous work showed that a JASMONATE ZIM-domain (JAZ) protein,… read more here.
Keywords: phenolic acid; miltiorrhiza; acid biosynthesis; acid ... See more keywords