Articles with "acid buffered" as a keyword



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Overcoming the Challenges of Low Drug Solubility in the Intravenous Formulation of Solithromycin.

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Published in 2018 at "Journal of pharmaceutical sciences"

DOI: 10.1016/j.xphs.2017.10.030

Abstract: Solithromycin is a fluoro-ketolide (a fourth-generation macrolide) antibiotic that has been undergoing clinical trials for the treatment of community-acquired bacterial pneumonia. In this study, development of the tri-amino acid-buffered solithromycin intravenous (IV) formulation was performed… read more here.

Keywords: buffered formulation; solithromycin; formulation; overcoming challenges ... See more keywords