The iron complex of dimethyl chlorin e 6 –thioctic acid conjugate and its monolayers on the water and gold surfaces
Sign Up to like & getrecommendations! Published in 2017 at "Mendeleev Communications"
DOI: 10.1016/j.mencom.2017.11.024
Abstract: A μ-oxo-Fe3+ complex of chlorin e6–thioctic acid conjugate was synthesized and explored as a new sensing material for nitric oxide. This conjugate can be used as a model for NO-binding potential biosensors. read more here.
Keywords: acid conjugate; chlorin thioctic; thioctic acid; conjugate ... See more keywords
Synthesis and biological evaluation of geldanamycin–ferulic acid conjugate as a potent Hsp90 inhibitor
Sign Up to like & getrecommendations! Published in 2019 at "RSC Advances"
DOI: 10.1039/c9ra08665j
Abstract: Compared to 17-AAG, LZY228 exhibited higher Hsp90 inhibitory activity in vitro and better antitumor activity in human breast carcinoma (MDA-MB-231) xenograft nude mice. read more here.
Keywords: biological evaluation; acid conjugate; evaluation geldanamycin; geldanamycin ferulic ... See more keywords
Anastrozole and related glucuronic acid conjugate are electrophilic species
Sign Up to like & getrecommendations! Published in 2022 at "Xenobiotica"
DOI: 10.1080/00498254.2022.2086503
Abstract: Abstract Anastrozole (ANA), is an inhibitor of non-steroidal aromatase, widely employed for the treatment of breast cancer. However, ANA-associated liver injury cases have been documented in the application of the drug. The major purposes of… read more here.
Keywords: glucuronic acid; related glucuronic; electrophilic species; anastrozole related ... See more keywords
Design and Preclinical Evaluation of Nicotine–Stearic Acid Conjugate-Loaded Solid Lipid Nanoparticles for Transdermal Delivery: A Technical Note
Sign Up to like & getrecommendations! Published in 2023 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics15041043
Abstract: This study aimed to develop and evaluate nicotine--stearic acid conjugate-loaded solid lipid nanoparticles (NSA-SLNs) for transdermal delivery in nicotine replacement therapy (NRT). Nicotine conjugation to stearic acid prior to SLN formulation greatly increased drug loading.… read more here.
Keywords: conjugate loaded; acid; nicotine stearic; stearic acid ... See more keywords
Chitosan-maleic acid conjugate as potential excipient candidate for oral drug delivery?
Sign Up to like & getrecommendations! Published in 2023 at "Future medicinal chemistry"
DOI: 10.4155/fmc-2022-0258
Abstract: Aim: To develop and evaluate chitosan-maleic acid conjugate. Methods: Maleic anhydride was attached to chitosan backbone via amide bond formation resulting in chitosan-maleic acid. After characterization of the product via 1H nuclear magnetic resonance, attenuated total… read more here.
Keywords: oral drug; chitosan maleic; maleic acid; drug delivery ... See more keywords