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Published in 2019 at "Parasitology Research"
DOI: 10.1007/s00436-019-06329-3
Abstract: Acanthamoeba castellanii belonging to the T4 genotype is an opportunistic pathogen which is associated with blinding eye keratitis and rare but fatal central nervous system infection. A. castellanii pose serious challenges in antimicrobial chemotherapy due…
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Keywords:
acanthamoeba castellanii;
oleic acid;
acid conjugated;
conjugated silver ... See more keywords
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Published in 2018 at "European journal of medicinal chemistry"
DOI: 10.1016/j.ejmech.2017.12.089
Abstract: Present work describes the in vitro antibacterial evaluation of some new amino acid conjugated antimicrobial drugs. Structural modification was attempted on the three existing antimicrobial pharmaceuticals namely trimethoprim, metronidazole, isoniazid. Twenty one compounds from seven series…
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Keywords:
amino;
amino acid;
inhibition;
conjugated antimicrobial ... See more keywords
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Published in 2017 at "Journal of pharmaceutical sciences"
DOI: 10.1016/j.xphs.2017.07.020
Abstract: An efficient gene carrier to the brain is required for successful gene therapy of ischemic stroke. In this study, deoxycholic acid-conjugated polyethylenimine (DA-PEI) was synthesized and evaluated as a heme oxygenase-1 (HO-1) gene carrier for…
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Keywords:
ischemic stroke;
polyethylenimine;
deoxycholic acid;
acid conjugated ... See more keywords
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Published in 2022 at "Inorganic chemistry"
DOI: 10.1021/acs.inorgchem.2c03138
Abstract: Herein, MOF-808 (MOF = metal-organic framework) based on zirconium tricarboxylate was synthesized to investigate the influence of decorating groups of folic acid-conjugated chitosan (CS-FA) on drug-delivery efficiency. Quercetin (QU) was loaded on nondecorated MOF-808 and…
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Keywords:
conjugated chitosan;
acid conjugated;
folic acid;
microscopy ... See more keywords
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Published in 2021 at "International Journal of Polymeric Materials and Polymeric Biomaterials"
DOI: 10.1080/00914037.2021.1931207
Abstract: S-nitroso-N-acetylpenicillamine (SNAP) and hydrophobic succinyl pyrene (SuPy) were conjugated to hyaluronic acid (HA) through cystamine dihydrochloride (Cys) linkers to synthesize NO-conjugated red...
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Keywords:
conjugated nitrothiol;
responsive hyaluronic;
acid conjugated;
reductive responsive ... See more keywords
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Published in 2023 at "Nanotechnology"
DOI: 10.1088/1361-6528/acd5d9
Abstract: Osteosarcoma (OS) is a primary malignant bone tumor that occurs mainly in adolescents. Researchers are devoting to develop combination therapy methods in a multifunctional nanoplatform for the treatment of osteosarcoma. The results of previous research…
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Keywords:
photothermal therapy;
mir 520a;
acid conjugated;
folic acid ... See more keywords
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Published in 2019 at "International Journal of Nanomedicine"
DOI: 10.2147/ijn.s218577
Abstract: Objective The study was designed to investigate the therapeutic potential of lactobionic acid (LA) conjugated quercetin (Q) loaded organically modified silica nanoparticles (LA-Q-ORMOSIL) with bulk quercetin to mitigate cyclophosphamide (CP) induced liver injury. Methodology Q-ORMOSIL…
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Keywords:
quercetin;
bulk quercetin;
lactobionic acid;
ormosil nanoparticles ... See more keywords
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Published in 2021 at "International Journal of Nanomedicine"
DOI: 10.2147/ijn.s297634
Abstract: Purpose Development of hyaluronic acid conjugated metformin-phospholipid sonocomplexes (HA-MPS), a biphasic complexation product compiled for enhancing both the lipophilicity and targeting potential of Metformin (MET) to CD44 receptors on pancreatic cancer. Methods MET was chemically…
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Keywords:
conjugated metformin;
metformin phospholipid;
hyaluronic acid;
biphasic complexation ... See more keywords
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Published in 2019 at "Anti-cancer agents in medicinal chemistry"
DOI: 10.2174/1871520619666190702145609
Abstract: PURPOSE Site specific and toxic free drug delivery is an interesting area of research. Nano-engineered drug delivery systems possess remarkable potential for effective treatment of various types of cancers. METHODS In this view, a novel…
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Keywords:
folic acid;
conjugated keratin;
acid conjugated;
cancer ... See more keywords
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Published in 2020 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2020.00922
Abstract: Excessive pigmentation and reduced elasticity are the major skin problems that dermatologists and cosmetologists address. Compounds that inhibit melanin production might contribute to improving skin problems. In this study, we investigated whether coumaric acid- and…
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Keywords:
caffeic acid;
acid conjugated;
coumaric acid;
conjugated peptides ... See more keywords