Theoretical study of formate, tartrate, tartronate, and glycolate production from 6-carbon trioxylate intermediate in the citric acid cycle
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Molecular Modeling"
DOI: 10.1007/s00894-019-4240-z
Abstract: Reaction pathways of side products (formate, glycolate, and tartronate) from dihydroxyfumarate (DHF) were theoretically investigated as DHF is an intermediate in the process of producing tartrates and oxalate from glyoxylate of the citric acid cycle.… read more here.
Keywords: citric acid; energy; acid cycle; reaction ... See more keywords
Differences in possible TCA cycle replenishing pathways in purple non-sulfur bacteria possessing glyoxylate pathway
Sign Up to like & getrecommendations! Published in 2018 at "Photosynthesis Research"
DOI: 10.1007/s11120-018-0581-1
Abstract: Pathways replenishing tricarboxylic acid cycle were divided into four major groups based on metabolite serving as source for oxaloacetic acid or other tricarboxylic acid cycle component synthesis. Using this metabolic map, the analysis of genetic… read more here.
Keywords: purple non; acid cycle; tricarboxylic acid; cycle ... See more keywords
Tricarboxylic Acid Cycle Activity and Remodeling of Glycerophosphocholine Lipids Support Cytokine Induction in Response to Fungal Patterns.
Sign Up to like & getrecommendations! Published in 2019 at "Cell reports"
DOI: 10.1016/j.celrep.2019.03.033
Abstract: Increased glycolysis parallels immune cell activation, but the role of pyruvate remains largely unexplored. We found that stimulation of dendritic cells with the fungal surrogate zymosan causes decreases of pyruvate, citrate, itaconate, and α-ketoglutarate, while… read more here.
Keywords: acid cycle; cytokine induction; tricarboxylic acid; acetyl coa ... See more keywords
Alternative Oxidase Isoforms Are Differentially Activated by Tricarboxylic Acid Cycle Intermediates1[OPEN]
Sign Up to like & getrecommendations! Published in 2017 at "Plant Physiology"
DOI: 10.1104/pp.17.01331
Abstract: In Arabidopsis, alternative oxidase activation is isoform specific, with AOX1A activated by oxaloacetate and 2-oxoglutarate, AOX1D solely by 2-oxoglutarate, and AOX1C insensitive to both. The cyanide-insensitive alternative oxidase (AOX) is a non-proton-pumping ubiquinol oxidase that… read more here.
Keywords: oxidase; alternative oxidase; acid cycle; tricarboxylic acid ... See more keywords
Oncometabolites: A New Paradigm for Oncology, Metabolism, and the Clinical Laboratory.
Sign Up to like & getrecommendations! Published in 2017 at "Clinical chemistry"
DOI: 10.1373/clinchem.2016.267666
Abstract: BACKGROUND Pediatric clinical laboratories commonly measure tricarboxylic acid cycle intermediates for screening, diagnosis, and monitoring of specific inborn errors of metabolism, such as organic acidurias. In the past decade, the same tricarboxylic acid cycle metabolites… read more here.
Keywords: acid cycle; oncometabolites new; tricarboxylic acid; new paradigm ... See more keywords
Hypoxia Induces Saturated Fatty Acids Accumulation and Reduces Unsaturated Fatty Acids Independently of Reverse Tricarboxylic Acid Cycle in L6 Myotubes
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2022.663625
Abstract: Obstructive sleep apnea syndrome, characterized by repetitive episodes of tissue hypoxia, is associated with several metabolic impairments. Role of fatty acids and lipids attracts attention in its pathogenesis for their metabolic effects. Parallelly, hypoxia-induced activation… read more here.
Keywords: unsaturated fatty; rtca; reverse tricarboxylic; fatty acids ... See more keywords
Effect of Citric Acid Cycle Genetic Variants and Their Interactions with Obesity, Physical Activity and Energy Intake on the Risk of Colorectal Cancer: Results from a Nested Case-Control Study in the UK Biobank
Sign Up to like & getrecommendations! Published in 2020 at "Cancers"
DOI: 10.3390/cancers12102939
Abstract: Simple Summary The citric acid cycle has a central role in the cellular energy metabolism and biosynthesis of macromolecules in the mitochondrial matrix. We identified the single nucleotide polymorphisms (SNPs) of the citrate acid cycle… read more here.
Keywords: citric acid; acid cycle; energy; colorectal cancer ... See more keywords
Metabolomics Analysis Coupled with Weighted Gene Co-Expression Network Analysis Unravels the Associations of Tricarboxylic Acid Cycle-Intermediates with Edible Pigments Produced by Monascus purpureus (Hong Qu)
Sign Up to like & getrecommendations! Published in 2022 at "Foods"
DOI: 10.3390/foods11142168
Abstract: Monascus azaphilones pigments (MonAzPs) produced by microbial fermentation are widely used as food chemicals for coloring and supplying beneficial biological attributes. In this study, a fermentation perturbation strategy was implemented by separately adding different amino… read more here.
Keywords: expression; analysis; gene; acid cycle ... See more keywords