3‐Hydroxyisobutyric acid dehydrogenase deficiency: Expanding the clinical spectrum and quantitation of D‐ and L‐3‐Hydroxyisobutyric acid by an LC–MS/MS method
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Inherited Metabolic Disease"
DOI: 10.1002/jimd.12486
Abstract: A deficiency of 3‐hydroxyisobutyric acid dehydrogenase (HIBADH) has been recently identified as a cause of primary 3‐hydroxyisobutyric aciduria in two siblings; the only previously recognized primary cause had been a deficiency of methylmalonic semialdehyde dehydrogenase,… read more here.
Keywords: hydroxyisobutyric acid; acid dehydrogenase; acid; clinical spectrum ... See more keywords
Expression, purification, and characterization of a membrane-bound d-amino acid dehydrogenase from Proteus mirabilis JN458
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DOI: 10.1007/s10529-017-2388-0
Abstract: AbstractObjectives To characterize a novel membrane-bound d-amino acid dehydrogenase from Proteus mirabilis JN458 (PmDAD).ResultsThe recombinant PmDAD protein, encoding a peptide of 434 amino acids with a MW of 47.7 kDa, exhibited broad substrate specificity with d-alanine… read more here.
Keywords: dehydrogenase; amino acid; acid dehydrogenase; dehydrogenase proteus ... See more keywords
Artificial Thermostable D-Amino Acid Dehydrogenase: Creation and Application
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2018.01760
Abstract: Many kinds of NAD(P)+-dependent L-amino acid dehydrogenases have been so far found and effectively used for synthesis of L-amino acids and their analogs, and for their sensing. By contrast, similar biotechnological use of D-amino acid… read more here.
Keywords: creation; amino; amino acid; acid dehydrogenase ... See more keywords