Biological functions of kojic acid and its derivatives in medicine, cosmetics, and food industry: Insights into health aspects
Sign Up to like & getrecommendations! Published in 2022 at "Archiv der Pharmazie"
DOI: 10.1002/ardp.202200215
Abstract: This review traces the road leading to the demonstration of a variety of kojic acid chemical and biological properties. It illustrates the biological effects of several synthetic kojic acid derivatives. Besides the main capability of… read more here.
Keywords: kojic acid; health; acid derivatives; medicine ... See more keywords
Terminal Alkenes from Acrylic Acid Derivatives via Non‐Oxidative Enzymatic Decarboxylation by Ferulic Acid Decarboxylases
Sign Up to like & getrecommendations! Published in 2018 at "Chemcatchem"
DOI: 10.1002/cctc.201800643
Abstract: Fungal ferulic acid decarboxylases (FDCs) belong to the UbiD‐family of enzymes and catalyse the reversible (de)carboxylation of cinnamic acid derivatives through the use of a prenylated flavin cofactor. The latter is synthesised by the flavin… read more here.
Keywords: acid decarboxylases; decarboxylation; acrylic acid; ferulic acid ... See more keywords
Selective Conversion of Furoic Acid Derivatives to Multi‐Substituted Furanacrylate by a Ruthenium Catalyst
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DOI: 10.1002/cctc.201901365
Abstract: Furanacrylate derivatives, as a class of multi‐substituted furan compounds, have been widely used in drug synthesis, organic functional materials, novel polymer monomers, etc. In this paper, direct alkenylation and decarboxylation‐alkenylation of furoic acid derivatives to… read more here.
Keywords: alkenylation; furoic acid; multi substituted; acid derivatives ... See more keywords
Palladium‐Catalyzed Highly Enantioselective Arylation of Cyclic N‐Sulfonyl α‐Ketimino Esters towards the Synthesis of α‐Quaternary Chiral Amino Acid Derivatives
Sign Up to like & getrecommendations! Published in 2019 at "ChemCatChem"
DOI: 10.1002/cctc.201901933
Abstract: We have developed a highly effective palladium/PHOX catalyst system for efficient asymmetric 1,2‐addition of arylboronic acids to six‐membered 1,2,6‐thiadiazine‐1,1‐dioxide type cyclic N‐sulfonyl α‐iminoesters. The protocol allows convenient synthesis of a variety of nearly optically pure… read more here.
Keywords: synthesis; amino acid; acid derivatives; cyclic sulfonyl ... See more keywords
Axially chiral hemiaminals from nonracemic α-amino acid derivatives (thiohydantoins): Synthesis and isomer identification.
Sign Up to like & getrecommendations! Published in 2020 at "Chirality"
DOI: 10.1002/chir.23274
Abstract: Stable, nonracemic axially chiral hemiaminals (O,N-hemiacetals) have been synthesized stereoselectively from lithium aluminum hydride (LiAlH4 ) reductions of nonracemic 5-methyl- and 5-isopropyl-3-(o-aryl)-2-thioydantoins in tetrahydrofuran (THF) at room temperature in 10 min. Predominantly S-configured hemiaminals at… read more here.
Keywords: nonracemic amino; amino acid; hemiaminals nonracemic; chiral hemiaminals ... See more keywords
Enantioselective synthesis of indole-based unnatural β-Alkynyl α-amino acid derivatives via chiral phosphoric acid catalysis.
Sign Up to like & getrecommendations! Published in 2022 at "Chirality"
DOI: 10.1002/chir.23422
Abstract: The synthesis of unnatural α-amino acid derivatives has attracted considerable interest in recent years, as they are ubiquitous in protein synthesis and peptide-based drug discovery. Herein, we reported the chiral phosphoric acid catalyzed asymmetric reaction… read more here.
Keywords: chiral phosphoric; synthesis; acid; amino acid ... See more keywords
Transition-Metal-Free Valorization of Biomass-derived Levulinic Acid Derivatives: Synthesis of Curcumene and Xanthorrhizol.
Sign Up to like & getrecommendations! Published in 2020 at "ChemSusChem"
DOI: 10.1002/cssc.202002167
Abstract: Levulinic acid (LA) is acknowledged one of the most promising biomass-derived platform molecules, and can be transformed into various value-added chemicals. Here, we report a new reaction process for the valorization of levulinic acid derivatives under transition-metal free condition. The… read more here.
Keywords: transition metal; biomass derived; levulinic acid; acid derivatives ... See more keywords
Medicinal chemistry of anthranilic acid derivatives: A mini review.
Sign Up to like & getrecommendations! Published in 2021 at "Drug development research"
DOI: 10.1002/ddr.21842
Abstract: Anthranilic acid and its analogues present a privileged profile as pharmacophores for the rational development of pharmaceuticals deliberated for managing the pathophysiology and pathogenesis of various diseases. The substitution on anthranilic acid scaffold provides large… read more here.
Keywords: derivatives anthranilic; chemistry; anthranilic acid; acid derivatives ... See more keywords
Novel acetic acid derivatives containing quinazolin‐4(3H)‐one ring: Synthesis, in vitro, and in silico evaluation of potent aldose reductase inhibitors
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DOI: 10.1002/ddr.22031
Abstract: Aldose reductase (AR) is a crucial enzyme of the polyol pathway through which glucose is metabolized under conditions of hyperglycemia related to diabetes. A series of novel acetic acid derivatives containing quinazolin‐4(3H)‐one ring (1–22) was… read more here.
Keywords: derivatives containing; acid; aldose reductase; acetic acid ... See more keywords
Fatty acid derivatives from the halotolerant fungus Cladosporium cladosporioides
Sign Up to like & getrecommendations! Published in 2018 at "Magnetic Resonance in Chemistry"
DOI: 10.1002/mrc.4659
Abstract: Halotolerant fungus Cladosporium cladosporioides OUCMDZ‐187 was isolated from the mangrove plant Rhizophora stylosa collected in Shankou, Guangxi Province of China. Three new fatty acid esters cladosporesters A–C (1–3) and 5 new fatty acids cladosporacids A–E… read more here.
Keywords: fatty acid; cladosporium cladosporioides; acid derivatives; halotolerant fungus ... See more keywords
Novel cinnamic acid derivatives as a versatile tool for developing agrochemicals for controlling plant virus and bacterial diseases by enhancing plant defense responses.
Sign Up to like & getrecommendations! Published in 2023 at "Pest management science"
DOI: 10.1002/ps.7433
Abstract: BACKGROUND The intractable plant pathogens have overwhelmingly inflicted yield and quality losses on crops worldwide. The discovery and exploration of novel agrochemical alternatives based on chemical modification of bioactive natural products is a high-efficiency approach.… read more here.
Keywords: virus; defense; cinnamic acid; plant ... See more keywords