Identification of Pyrrolidine‐3‐acetic Acid Derived Oximes as Potent Inhibitors of γ‐Aminobutyric Acid Transporter 1 through Library Screening with MS Binding Assays
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DOI: 10.1002/cmdc.201800556
Abstract: In this study, pyrrolidine‐3‐acetic acid derived oxime libraries were applied to the concept of library screening by MS Binding Assays, as a powerful technique to reveal new potent murine γ‐aminobutyric acid transporter subtype (mGAT1) inhibitors.… read more here.
Keywords: acid derived; pyrrolidine acetic; binding assays; acetic acid ... See more keywords
Experimental and Computational Evaluation of Piperonylic Acid Derived Hydrazones Bearing Isatin Moieties as Dual Inhibitors of Cholinesterases and Monoamine Oxidases
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DOI: 10.1002/cmdc.201900277
Abstract: A set of piperonylic acid derived hydrazones with variable isatin moieties was synthesized and evaluated for their inhibitory activity against the enzymes acetylcholinesterase (AChE), butyrylcholinesterase (BChE), and monoamine oxidases A and B (MAO‐A/B). The results… read more here.
Keywords: derived hydrazones; acid derived; isatin moieties; piperonylic acid ... See more keywords
Humic acid-derived graphene–SnO2 nanocomposites for high capacity lithium-ion battery anodes
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Materials Science: Materials in Electronics"
DOI: 10.1007/s10854-018-8858-x
Abstract: Humic acid obtained from wood, soil, and coal provides a naturally occurring highly oxidized carbonaceous two-dimensional material. Humic acid obtained from Leonardite coal and tin(II) chloride were used to synthesize graphene–SnO2 nanocomposites using scalable, thermal… read more here.
Keywords: acid derived; graphene sno2; acid; humic acid ... See more keywords
Biosynthesis of fatty acid-derived hydrocarbons: perspectives on enzymology and enzyme engineering.
Sign Up to like & getrecommendations! Published in 2019 at "Current opinion in biotechnology"
DOI: 10.1016/j.copbio.2019.07.005
Abstract: Enormous fuel consumption and growing environmental concerns have been spurring development of renewable biofuels. Among various biofuels, fatty acid-derived biohydrocarbons are ideal alternatives to non-renewable fossil fuels due to their closest properties to petroleum-based fuels.… read more here.
Keywords: biosynthesis fatty; acid derived; derived hydrocarbons; fatty acid ... See more keywords
Enzymology and biosynthesis of the orsellinic acid derived medicinal meroterpenoids.
Sign Up to like & getrecommendations! Published in 2020 at "Current opinion in biotechnology"
DOI: 10.1016/j.copbio.2020.11.016
Abstract: The advent of synthetic biology has yielded fruitful studies on orsellinic acid-derived meroterpenoids, which reportedly possess important biological activities. Genomics and transcriptomics have significantly accelerated the discovery of the biosynthetic genes for orsellinic acid-derived fungal… read more here.
Keywords: acid derived; orsellinic acid; enzymology biosynthesis; enzymology ... See more keywords
Temperature induced self-assembly of amino acid-derived vinyl block copolymers via dual phase transitions.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of colloid and interface science"
DOI: 10.1016/j.jcis.2017.04.027
Abstract: The unique thermoresponsive phase behaviors of diblock copolymers from amino acid-derived vinyl monomers have been demonstrated in view of variation in the aggregation state in water. Amino acid-based block copolymers composed of N-acryloyl-Ala-methylester (NAAMe) and… read more here.
Keywords: phase; acid derived; amino acid; block ... See more keywords
Control of Bird Feeding Behavior by Tannin1 through Modulating the Biosynthesis of Polyphenols and Fatty Acid-Derived Volatiles in Sorghum.
Sign Up to like & getrecommendations! Published in 2019 at "Molecular plant"
DOI: 10.1016/j.molp.2019.08.004
Abstract: Bird predation during seed maturation causes great loss to agricultural production. In this study, by GWAS analysis of a large-scale sorghum germplasm diversity panel we identified Tannin1, which encodes a WD40 protein functioning in the… read more here.
Keywords: bird feeding; acid derived; feeding behavior; fatty acid ... See more keywords
Synthesis and cytotoxicity of betulin and betulinic acid derived 30-oxo-amides
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DOI: 10.1016/j.steroids.2022.109014
Abstract: Betulin and betulinic acid derived 30-oxo-amides were prepared by hydroboration, subsequent oxidation and amidation; these novel compounds were screened for their cytotoxic activity by SRB assays. All of the compounds showed significant cytotoxic activity for… read more here.
Keywords: betulinic acid; oxo amides; derived oxo; betulin betulinic ... See more keywords
A convenient synthesis of amino acid-derived precursors to the important wine aroma 3-sulfanylhexan-1-ol (3SH)
Sign Up to like & getrecommendations! Published in 2020 at "Tetrahedron Letters"
DOI: 10.1016/j.tetlet.2020.151663
Abstract: Abstract A convenient, straightforward synthesis of the important amino acid-derived aroma precursors, 3-S-cysteinylhexan-1-ol (Cys-3SH) and 3-S-glutathionylhexan-1-ol (GSH-3SH) from commercially available butan-1-ol is reported. The versatility of this approach to include deuterium labelling is also demonstrated. read more here.
Keywords: convenient synthesis; acid derived; amino acid;
Engineering a bacterial platform for total biosynthesis of caffeic acid derived phenethyl esters and amides.
Sign Up to like & getrecommendations! Published in 2017 at "Metabolic engineering"
DOI: 10.1016/j.ymben.2017.09.011
Abstract: Caffeic acid has been widely recognized as a versatile pharmacophore for synthesis of new chemical entities, among which caffeic acid derived phenethyl esters and amides are the most extensively-investigated bioactive compounds with potential therapeutical applications.… read more here.
Keywords: caffeic acid; acid derived; derived phenethyl; phenethyl esters ... See more keywords
Peptide-Functionalized Amino Acid-Derived Pseudoprotein-Based Hydrogel with Hemorrhage Control and Antibacterial Activity for Wound Healing
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DOI: 10.1021/acs.chemmater.9b00850
Abstract: Developing permanent antibacterial and rapid hemostatic wound dressings with excellent biocompatibility is urgently needed and has always gained great attention. Here, a series of amino acid-derived pseudoprotein consisting of poly(ester amide) (PEA)-based hydrogel dressings and… read more here.
Keywords: peptide functionalized; acid derived; based hydrogel; amino acid ... See more keywords