Stretch‐driven microfluidic chip for nucleic acid detection
Sign Up to like & getrecommendations! Published in 2021 at "Biotechnology and Bioengineering"
DOI: 10.1002/bit.27839
Abstract: Molecular diagnosis is an essential means to detect pathogens. The portable nucleic acid detection chip has excellent prospects in places where medical resources are scarce, and it is also of research interest in the field… read more here.
Keywords: microfluidic chip; detection; chip nucleic; acid detection ... See more keywords
Improved Strategies for CRISPR-Cas12-based Nucleic Acids Detection
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Analysis and Testing"
DOI: 10.1007/s41664-022-00212-4
Abstract: The COVID-19 pandemic has brought great challenges to traditional nucleic acid detection technology. Thus, it is urgent to develop a more simple and efficient nucleic acid detection technology. CRISPR-Cas12 has signal amplification ability, high sensitivity… read more here.
Keywords: based nucleic; detection; cas12 based; nucleic acid ... See more keywords
The point-of-care-testing of nucleic acids by chip, cartridge and paper sensors
Sign Up to like & getrecommendations! Published in 2021 at "Chinese Chemical Letters"
DOI: 10.1016/j.cclet.2021.06.025
Abstract: ABSTRACT Point-of-care nucleic acid testing (POCNAT) has played an important role in the outbreak of infectious diseases (e.g., COVID-19) over recent years. POCNAT aims to realize the rapid, simple and automatic detection of nucleic acid.… read more here.
Keywords: acid detection; nucleic acid; point care; technology ... See more keywords
The why and how of amino acid analytics in cancer diagnostics and therapy.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of biotechnology"
DOI: 10.1016/j.jbiotec.2016.12.001
Abstract: Pathological alterations in cell functions are frequently accompanied by metabolic reprogramming including modifications in amino acid metabolism. Amino acid detection is thus integral to the diagnosis of many hereditary metabolic diseases. The development of malignant… read more here.
Keywords: cancer; acid detection; amino acid; acid analytics ... See more keywords
An ultrasensitive electrochemiluminescence assay for nucleic acid detection based on carboxyl functionalized polymer dots
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Electroanalytical Chemistry"
DOI: 10.1016/j.jelechem.2021.115743
Abstract: Abstract An electrochemiluminescence (ECL) sensing platform for ultrasensitive detection of miRNA-122 was developed by integrating novel emitters of polymer dots (Pdots) and signal amplification strategies. Firstly, we synthesized a novel polymer with carboxyl group which… read more here.
Keywords: polymer dots; detection; electrochemiluminescence; acid detection ... See more keywords
In situ formation of Ag/Au nanorods as a platform to design a non-aggregation colorimetric assay for uric acid detection in biological fluids
Sign Up to like & getrecommendations! Published in 2020 at "Microchemical Journal"
DOI: 10.1016/j.microc.2020.104642
Abstract: Abstract Herein, we report on a sensitive probe for colorimetric detection of uric acid based on the formation of Ag shell on Au nanorods (Ag/AuNRs) in the presence of uric acid. Uric acid can reduce… read more here.
Keywords: acid detection; uric acid; acid; situ formation ... See more keywords
Specificity Enhancement of Deoxyribonucleic Acid Polymerization for Sensitive Nucleic Acid Detection.
Sign Up to like & getrecommendations! Published in 2020 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.0c03223
Abstract: Specificity of DNA polymerization plays a critical role in DNA replication and storage of genetic information. Likewise, biotechnological applications, such as nucleic acid detection, DNA amplification, and gene cloning, require high specificity in DNA synthesis… read more here.
Keywords: polymerization; dna; acid detection; nucleic acid ... See more keywords
Automated Microfluidic Nucleic Acid Detection Platform-Integrated RPA-T7-Cas13a for Pathogen Diagnosis.
Sign Up to like & getrecommendations! Published in 2023 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.3c00242
Abstract: There is a growing urgent need for point-of-care testing (POCT) devices that integrate sample pretreatment and nucleic acid detection in a rapid, economical, and non-labor-intensive way. Here, we have developed an automated, portable nucleic acid… read more here.
Keywords: acid detection; rpa cas13a; detection; nucleic acid ... See more keywords
Magnetic-Responsive Surface-Enhanced Raman Scattering Platform with Tunable Hot Spot for Ultrasensitive Virus Nucleic Acid Detection.
Sign Up to like & getrecommendations! Published in 2022 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.1c21173
Abstract: Surface-enhanced Raman scattering (SERS)-based biosensors are promising tools for virus nucleic acid detection. However, it remains challenging for SERS-based biosensors using a sandwiching strategy to detect long-chain nucleic acids such as nucleocapsid (N) gene of… read more here.
Keywords: platform; surface enhanced; detection; nucleic acid ... See more keywords
Rotary Valve-Assisted Fluidic System Coupling with CRISPR/Cas12a for Fully Integrated Nucleic Acid Detection.
Sign Up to like & getrecommendations! Published in 2021 at "ACS sensors"
DOI: 10.1021/acssensors.1c01468
Abstract: Of late, many nucleic acid analysis platforms have been established, but there is still room for constructing integrated nucleic acid detection systems with high nucleic acid extraction efficiency, low detection cost, and convenient operation. In… read more here.
Keywords: integrated nucleic; detection; acid detection; nucleic acid ... See more keywords
CRISPR-Cas12a-assisted nucleic acid detection
Sign Up to like & getrecommendations! Published in 2018 at "Cell Discovery"
DOI: 10.1038/s41421-018-0028-z
Abstract: Dear Editor, Today, the need for time-effective and cost-effective nucleic acid detection methods is still growing in fields such as human genotyping and pathogen detection. Using synthetic biomolecular components, many methods have been developed for… read more here.
Keywords: target dna; detection; crispr; cas12a ... See more keywords