The STING agonist 5,6-dimethylxanthenone-4-acetic acid (DMXAA) stimulates an antiviral state and protects mice against herpes simplex virus-induced neurological disease.
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DOI: 10.1016/j.virol.2019.01.006
Abstract: Herpes simplex virus (HSV)- 1 is the most common cause of sporadic viral encephalitis and accounts for 5-10% of cases worldwide. A key factor in host control of viral infection is the initiation of the interferon… read more here.
Keywords: dimethylxanthenone acetic; dmxaa; acetic acid; herpes simplex ... See more keywords