Articles with "acid drugs" as a keyword



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Chemical modifications of nucleic acid drugs and their delivery systems for gene‐based therapy

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Published in 2018 at "Medicinal Research Reviews"

DOI: 10.1002/med.21479

Abstract: Gene‐based therapy is one of essential therapeutic strategies for precision medicine through targeting specific genes in specific cells of target tissues. However, there still exist many problems that need to be solved, such as safety,… read more here.

Keywords: delivery; acid drugs; gene based; based therapy ... See more keywords
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Multistage-Responsive Nanocomplexes Attenuate Ulcerative Colitis by Improving the Accumulation and Distribution of Oral Nucleic Acid Drugs in the Colon.

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Published in 2022 at "ACS applied materials & interfaces"

DOI: 10.1021/acsami.1c21595

Abstract: Oral gene therapy has emerged as a potential optimal treatment for ulcerative colitis (UC). Nucleic acid drugs possessing versatility can not only inhibit inflammation but realize colon mucosal healing, fulfilling the clinical objective of UC… read more here.

Keywords: acid drugs; drugs colon; accumulation; nucleic acid ... See more keywords