A Strong Hybrid Fatty Acid Inducible Transcriptional Sensor Built From Yarrowia lipolytica Upstream Activating and Regulatory Sequences
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DOI: 10.1002/biot.201700248
Abstract: The engineering of Yarrowia lipolytica to accumulate lipids with high titers and productivities has been enabled with a handful of constitutive promoters for pathway engineering. However, the development of promoters that are both strong and… read more here.
Keywords: hybrid fatty; fatty acid; strong hybrid; acid inducible ... See more keywords
Inhibition of Glycolysis Impairs Retinoic Acid-Inducible Gene I–Mediated Antiviral Responses in Primary Human Dendritic Cells
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DOI: 10.3389/fcimb.2022.910864
Abstract: Dendritic cells (DCs) are important mediators of the induction and regulation of adaptive immune responses following microbial infection and inflammation. Sensing environmental danger signals including viruses, microbial products, or inflammatory stimuli by DCs leads to… read more here.
Keywords: primary human; retinoic acid; glycolysis; inducible gene ... See more keywords
Immune Regulator Retinoic Acid-Inducible Gene I (RIG-I) in the Pathogenesis of Cardiovascular Disease
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DOI: 10.3389/fimmu.2022.893204
Abstract: Retinoic acid-inducible gene I (RIG-I) is a cytosolic pattern recognition receptor that contains two CARD domains, an RNA helicase domain, and a C-terminal domain. RIG-I initiates antiviral innate immunity by recognizing exogenous viral RNAs/DNAs. However,… read more here.
Keywords: gene rig; retinoic acid; acid inducible; inducible gene ... See more keywords