pH-sensitive carboxymethyl chitosan hydrogels via acid-labile ortho ester linkage for potential biomedical applications.
Sign Up to like & getrecommendations! Published in 2017 at "Carbohydrate polymers"
DOI: 10.1016/j.carbpol.2017.09.004
Abstract: Hydrogel systems with favorable biocompatibility and biodegradability are of much interest for application in biomaterials and tissue engineering. In this study, a new ortho ester-based acid-labile crosslink agent with dual-epoxy end groups was synthesized and… read more here.
Keywords: ortho ester; acid labile; carboxymethyl chitosan;
Smart supramolecular vesicles based on glutathione-reactive pillar[6]arene and acid-labile prodrug: Dual drug loading and sequential release
Sign Up to like & getrecommendations! Published in 2021 at "Chinese Chemical Letters"
DOI: 10.1016/j.cclet.2021.07.024
Abstract: Abstract Glutathione thiol-reactive pillar[6]arene (TWP6) is designed and synthesized as the first example of reducing agent-reactive host molecule. TWP6 shows high affinity binding towards suitable anti-tumor drugs and guests. Doxorubicin-based acid-labile prodrugs and TWP6 are… read more here.
Keywords: reactive pillar; sequential release; pillar arene; acid labile ... See more keywords
Mass Spectrometric Characterization of an Acid-Labile Adduct Formed with 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine and Albumin in Humans.
Sign Up to like & getrecommendations! Published in 2017 at "Chemical research in toxicology"
DOI: 10.1021/acs.chemrestox.6b00426
Abstract: 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) is a carcinogenic heterocyclic aromatic amine formed during the high-temperature cooking of meats. The cytochrome P450-mediated N-hydroxylation of the exocyclic amine group of PhIP produces 2-hydroxyamino-1-methyl-6-phenylimidazo[4,5-b]pyridine, an electrophilic metabolite that forms adducts with… read more here.
Keywords: phip; acid labile; phenylimidazo pyridine; albumin ... See more keywords
Acid-Induced Intracellular Dissociation of β-Cyclodextrin-Threaded Polyrotaxanes Directed toward Attenuating Phototoxicity of Bisretinoids through Promoting Excretion.
Sign Up to like & getrecommendations! Published in 2017 at "Molecular pharmaceutics"
DOI: 10.1021/acs.molpharmaceut.7b00859
Abstract: In the retinal pigment epithelium of patients with age-related macular degeneration (AMD), excess N-retinylidene-N-retinylethanolamine (A2E), a dimer of all-trans-retinal, accumulats to induce inflammatory cytokine secretion and phototoxic effects. Therefore, the reduction of intracellular A2E is… read more here.
Keywords: threaded polyrotaxanes; cyclodextrin threaded; acid labile; prxs ... See more keywords
Stereostructure Clarifying Total Synthesis of the (Polyenoyl)tetramic Acid Militarinone B. A Highly Acid-Labile N-Protecting Group for Amides†.
Sign Up to like & getrecommendations! Published in 2021 at "Organic letters"
DOI: 10.1021/acs.orglett.1c01652
Abstract: The 5S, 8'R, and 10'R configurations of militarinone B (3), which is a natural product from Paecilomyces militaris, should equal those in its biosynthetic precursor, militarinone C. The configuration at C-1' emerged from syntheses of… read more here.
Keywords: labile protecting; militarinone; acid labile; protecting group ... See more keywords
Waterproof Cellulose-Based Substrates for In-Drop Plasmonic Colorimetric Sensing of Volatiles: Application to Acid-Labile Sulfide Determination in Waters
Sign Up to like & getrecommendations! Published in 2022 at "ACS Sensors"
DOI: 10.1021/acssensors.1c02585
Abstract: The present work reports on the assessment of widely available waterproof cellulose-based substrates for the development of sensitive in-drop plasmonic sensing approaches. The applicability of three inexpensive substrates, namely, Whatman 1PS, polyethylene-coated filter paper, and… read more here.
Keywords: cellulose based; acid labile; based substrates; drop plasmonic ... See more keywords
The blood level of acid-labile subunit in short children born small for gestational age with normosomatotropinemia
Sign Up to like & getrecommendations! Published in 2020 at "INTERNATIONAL JOURNAL OF ENDOCRINOLOGY"
DOI: 10.22141/2224-0721.16.1.2020.199125
Abstract: Актуальность. Недостаточный для гестационного возраста рост составляет примерно 20 % от всех случаев низкорослости у детей. Несмотря на то, что у большинства детей с задержкой внутриутробного развития (ЗВУР) отмечается скачок роста в раннем детстве (в течение… read more here.
Keywords: labile subunit; level acid; blood level; acid labile ... See more keywords