Structural Characterization of Co-Crystals of Chlordiazepoxide with p-Aminobenzoic Acid and Lorazepam with Nicotinamide by DSC, X-ray Diffraction, FTIR and Raman Spectroscopy
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DOI: 10.3390/pharmaceutics12070648
Abstract: The low water solubility of benzodiazepines seriously affects their bioavailability and, in consequence, their biological activity. Since co-crystallization has been found to be a promising way to modify undesirable properties in active pharmaceutical ingredients, the… read more here.
Keywords: acid lorazepam; ray diffraction; aminobenzoic acid; diffraction ... See more keywords