Irinotecan‐induced bile acid malabsorption is associated with down‐regulation of ileal Asbt (Slc10a2) in mice
Sign Up to like & getrecommendations! Published in 2017 at "European Journal of Pharmaceutical Sciences"
DOI: 10.1016/j.ejps.2017.03.012
Abstract: &NA; Irinotecan, (CPT‐11), an antitumor agent primarily used for the treatment of solid tumors, has often compromised clinical application due to the inducement of severe delay‐onset diarrhea. Bile acid malabsorption (BAM) is widely accepted as… read more here.
Keywords: cpt; treatment; asbt; acid malabsorption ... See more keywords
eP230 A review of the spectrum of causes of Bile Acid Malabsorption – does cholecystectomy play a significant part?
Sign Up to like & getrecommendations! Published in 2025 at "British Journal of Surgery"
DOI: 10.1093/bjs/znaf166.446
Abstract: Bile acid malabsorption (BAM) arises from dysregulation of enterohepatic bile acid recycling/ production, manifesting as chronic Bile acid diarrhoea (BAD). This is Type 2 BAD (previously idiopathic/Primary BAM) with no small bowel (SB) disorder, Type… read more here.
Keywords: spectrum causes; post; bile acid; cholecystectomy ... See more keywords
Biomarkers for Bile Acid Malabsorption in Diarrhea-predominant Irritable Bowel Syndrome
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Clinical Gastroenterology"
DOI: 10.1097/mcg.0000000000001841
Abstract: Background and Aim: A clear relationship of biological indexes between bile acid malabsorption (BAM) and diarrhea-predominant irritable bowel syndrome (IBS-D) has not been well analyzed. This meta-analysis aimed to establish a more convenient method to… read more here.
Keywords: diarrhea predominant; ibs patients; irritable bowel; acid malabsorption ... See more keywords
Bile acid malabsorption is associated with diarrhea in acute phase of colitis.
Sign Up to like & getrecommendations! Published in 2018 at "Canadian journal of physiology and pharmacology"
DOI: 10.1139/cjpp-2018-0017
Abstract: The enterohepatic circulation of bile acids (BAs) critically depends on BA transporters and enzymes, which can be affected by inflammatory bowel disease. Diarrhea in colitis is believed to result in part from BA malabsorption. The… read more here.
Keywords: phase; colitis; malabsorption; transporters enzymes ... See more keywords
Fecal microbiota transplantation improves bile acid malabsorption in patients with inflammatory bowel disease: results of microbiota and metabolites from two cohort studies
Sign Up to like & getrecommendations! Published in 2025 at "BMC Medicine"
DOI: 10.1186/s12916-025-04353-y
Abstract: Bile acid malabsorption (BAM) or bile acid diarrhea (BAD) complicates more than 30% of Crohn’s disease (CD), yet no non-invasive biomarker reliably identifies patients who will benefit from fecal microbiota transplantation (FMT). We investigated whether… read more here.
Keywords: disease; bile acid; acid malabsorption; fecal microbiota ... See more keywords
The efficacy of a low-fat diet to manage the symptoms of bile acid malabsorption – outcomes in patients previously treated for cancer
Sign Up to like & getrecommendations! Published in 2017 at "Clinical Medicine"
DOI: 10.7861/clinmedicine.17-5-412
Abstract: ABSTRACT Dietary fat ingestion triggers bile secretion into the gastrointestinal tract. Bile acid malabsorption affects >1% of the population, causing loose stool and other gastrointestinal symptoms. The diagnosis is frequently missed. Treatments are often considered… read more here.
Keywords: low fat; dietary intervention; acid malabsorption; efficacy low ... See more keywords
What is the cost of delayed diagnosis of bile acid malabsorption?
Sign Up to like & getrecommendations! Published in 2019 at "Clinical Medicine"
DOI: 10.7861/clinmedicine.19-2-s55
Abstract: To evaluate the cost of delayed diagnosis of bile acid malabsorption (BAM). The notes of all patients undergoing selenium-75 taurocholic acid (SeHCAT) scanning in our trust over a 1-year period were reviewed retrospectively. The number… read more here.
Keywords: bile acid; diagnosis bile; cost delayed; acid malabsorption ... See more keywords