Articles with "acid metabolites" as a keyword



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Bile acid metabolites in early pregnancy and risk of gestational diabetes in Chinese women: A nested case-control study

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Published in 2018 at "EBioMedicine"

DOI: 10.1016/j.ebiom.2018.08.015

Abstract: Background Bile acid metabolism plays an important role in metabolism but it is uncertain whether bile acid metabolites in early pregnancy are associated with risk of gestational diabetes mellitus (GDM). Methods We organized a 1:1… read more here.

Keywords: risk; early pregnancy; acid metabolites; acid ... See more keywords
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Initial military training modulates serum fatty acid and amino acid metabolites

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Published in 2022 at "Physiological Reports"

DOI: 10.14814/phy2.15385

Abstract: Initial military training (IMT) results in increased fatā€free mass (FFM) and decreased fat mass (FM). The underlying metabolic adaptations facilitating changes in body composition during IMT are unknown. The objective of this study was to… read more here.

Keywords: body composition; acid; amino acid; acid metabolites ... See more keywords
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Serum organic acid metabolites can be used as potential biomarkers to identify prostatitis, benign prostatic hyperplasia, and prostate cancer

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Published in 2023 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2022.998447

Abstract: Background Noninvasive methods for the early identify diagnosis of prostatitis, benign prostatic hyperplasia (BPH), and prostate cancer (PCa) are current clinical challenges. Methods The serum metabolites of 20 healthy individuals and patients with prostatitis, BPH,… read more here.

Keywords: prostatitis; diagnostic models; acid; organic acid ... See more keywords
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Fatty acid metabolites of Dendrobium nobile were positively correlated with representative endophytic fungi at altitude

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Published in 2023 at "Frontiers in Microbiology"

DOI: 10.3389/fmicb.2023.1128956

Abstract: Introduction Altitude, as a comprehensive ecological factor, regulates the growth and development of plants and microbial distribution. Dendrobium nobile (D. nobile) planted in habitats at different elevations in Chishui city, also shows metabolic differences and… read more here.

Keywords: altitude; dendrobium nobile; endophytic fungi; acid metabolites ... See more keywords
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Ganoderic Acid A Metabolites and Their Metabolic Kinetics

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Published in 2017 at "Frontiers in Pharmacology"

DOI: 10.3389/fphar.2017.00101

Abstract: Ganoderic acid A (GAA), a representative active triterpenoid from Ganoderma lucidum, has been reported to exhibit antinociceptive, antioxidative, cytotoxic, hepatoprotective and anticancer activities. The present study aims (1) to identify GAA metabolites, in vivo by… read more here.

Keywords: metabolites metabolic; ganoderic acid; acid metabolites; gaa ... See more keywords
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Dissecting the Regulation of Arachidonic Acid Metabolites by Uncaria rhynchophylla (Miq). Miq. in Spontaneously Hypertensive Rats and the Predictive Target sEH in the Anti-Hypertensive Effect Based on Metabolomics and Molecular Docking

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Published in 2022 at "Frontiers in Pharmacology"

DOI: 10.3389/fphar.2022.909631

Abstract: Uncaria rhynchophylla (Miq). Miq. (UR), as a traditional Chinese medicine, was employed in treating hypertension as a safe and effective therapy. The pharmacological properties of UR have characteristics of multiple biological targets and multiple functional… read more here.

Keywords: effect; hypertension; miq; acid metabolites ... See more keywords
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Systemic Metabolomic Profiles in Adult Patients with Bacterial Sepsis: Characterization of Patient Heterogeneity at the Time of Diagnosis

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Published in 2023 at "Biomolecules"

DOI: 10.3390/biom13020223

Abstract: Sepsis is a dysregulated host response to infection that causes potentially life-threatening organ dysfunction. We investigated the serum metabolomic profile at hospital admission for patients with bacterial sepsis. The study included 60 patients; 35 patients… read more here.

Keywords: sepsis; time; bacterial sepsis; amino acid ... See more keywords
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Amino Acid Metabolites Associated with Chronic Kidney Disease: An Eight-Year Follow-Up Korean Epidemiology Study

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Published in 2020 at "Biomedicines"

DOI: 10.3390/biomedicines8070222

Abstract: The discovery of metabolomics-based biomarkers has been a focus of recent kidney dysfunction research. In the present study, we aimed to identify metabolites associated with chronic kidney disease (CKD) in the general population using a… read more here.

Keywords: amino acid; study; metabolites associated; epidemiology ... See more keywords
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Membrane Lipid Derivatives: Roles of Arachidonic Acid and Its Metabolites in Pancreatic Physiology and Pathophysiology

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Published in 2023 at "Molecules"

DOI: 10.3390/molecules28114316

Abstract: One of the most important constituents of the cell membrane is arachidonic acid. Lipids forming part of the cellular membrane can be metabolized in a variety of cellular types of the body by a family… read more here.

Keywords: physiology; acid metabolites; arachidonic acid; membrane lipid ... See more keywords
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Ellagic Acid and Its Metabolites as Potent and Selective Allosteric Inhibitors of Liver Pyruvate Kinase

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Published in 2023 at "Nutrients"

DOI: 10.3390/nu15030577

Abstract: Liver pyruvate kinase (PKL) has recently emerged as a new target for non-alcoholic fatty liver disease (NAFLD), and inhibitors of this enzyme could represent a new therapeutic option. However, this breakthrough is complicated by selectivity… read more here.

Keywords: kinase; liver pyruvate; metabolites potent; ellagic acid ... See more keywords