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Published in 2018 at "EBioMedicine"
DOI: 10.1016/j.ebiom.2018.08.015
Abstract: Background Bile acid metabolism plays an important role in metabolism but it is uncertain whether bile acid metabolites in early pregnancy are associated with risk of gestational diabetes mellitus (GDM). Methods We organized a 1:1…
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Keywords:
risk;
early pregnancy;
acid metabolites;
acid ... See more keywords
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Published in 2022 at "Physiological Reports"
DOI: 10.14814/phy2.15385
Abstract: Initial military training (IMT) results in increased fatāfree mass (FFM) and decreased fat mass (FM). The underlying metabolic adaptations facilitating changes in body composition during IMT are unknown. The objective of this study was to…
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Keywords:
body composition;
acid;
amino acid;
acid metabolites ... See more keywords
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Published in 2023 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.998447
Abstract: Background Noninvasive methods for the early identify diagnosis of prostatitis, benign prostatic hyperplasia (BPH), and prostate cancer (PCa) are current clinical challenges. Methods The serum metabolites of 20 healthy individuals and patients with prostatitis, BPH,…
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Keywords:
prostatitis;
diagnostic models;
acid;
organic acid ... See more keywords
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Published in 2023 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2023.1128956
Abstract: Introduction Altitude, as a comprehensive ecological factor, regulates the growth and development of plants and microbial distribution. Dendrobium nobile (D. nobile) planted in habitats at different elevations in Chishui city, also shows metabolic differences and…
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Keywords:
altitude;
dendrobium nobile;
endophytic fungi;
acid metabolites ... See more keywords
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Published in 2017 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2017.00101
Abstract: Ganoderic acid A (GAA), a representative active triterpenoid from Ganoderma lucidum, has been reported to exhibit antinociceptive, antioxidative, cytotoxic, hepatoprotective and anticancer activities. The present study aims (1) to identify GAA metabolites, in vivo by…
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Keywords:
metabolites metabolic;
ganoderic acid;
acid metabolites;
gaa ... See more keywords
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Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.909631
Abstract: Uncaria rhynchophylla (Miq). Miq. (UR), as a traditional Chinese medicine, was employed in treating hypertension as a safe and effective therapy. The pharmacological properties of UR have characteristics of multiple biological targets and multiple functional…
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Keywords:
effect;
hypertension;
miq;
acid metabolites ... See more keywords
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Published in 2023 at "Biomolecules"
DOI: 10.3390/biom13020223
Abstract: Sepsis is a dysregulated host response to infection that causes potentially life-threatening organ dysfunction. We investigated the serum metabolomic profile at hospital admission for patients with bacterial sepsis. The study included 60 patients; 35 patients…
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Keywords:
sepsis;
time;
bacterial sepsis;
amino acid ... See more keywords
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Published in 2020 at "Biomedicines"
DOI: 10.3390/biomedicines8070222
Abstract: The discovery of metabolomics-based biomarkers has been a focus of recent kidney dysfunction research. In the present study, we aimed to identify metabolites associated with chronic kidney disease (CKD) in the general population using a…
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Keywords:
amino acid;
study;
metabolites associated;
epidemiology ... See more keywords
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Published in 2023 at "Molecules"
DOI: 10.3390/molecules28114316
Abstract: One of the most important constituents of the cell membrane is arachidonic acid. Lipids forming part of the cellular membrane can be metabolized in a variety of cellular types of the body by a family…
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Keywords:
physiology;
acid metabolites;
arachidonic acid;
membrane lipid ... See more keywords
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Published in 2023 at "Nutrients"
DOI: 10.3390/nu15030577
Abstract: Liver pyruvate kinase (PKL) has recently emerged as a new target for non-alcoholic fatty liver disease (NAFLD), and inhibitors of this enzyme could represent a new therapeutic option. However, this breakthrough is complicated by selectivity…
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Keywords:
kinase;
liver pyruvate;
metabolites potent;
ellagic acid ... See more keywords