Design, synthesis and biological evaluation of novel diosgenin–benzoic acid mustard hybrids with potential anti-proliferative activities in human hepatoma HepG2 cells
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DOI: 10.1080/14756366.2022.2070161
Abstract: Abstract To discover new lead compounds with anti-tumour activities, in the present study, natural diosgenin was hybridised with the reported benzoic acid mustard pharmacophore. The in vitro cytotoxicity of the resulting newly synthesised hybrids (8–10,… read more here.
Keywords: diosgenin; benzoic acid; acid mustard; hepg2 cells ... See more keywords