Dually Crosslinked Copper-Poly (Tannic Acid) Nanoparticles with Microenvironment-Responsiveness for Infected Wound Treatment.
Sign Up to like & getrecommendations! Published in 2023 at "Advanced healthcare materials"
DOI: 10.1002/adhm.202203063
Abstract: Reducing the burden of death due to wound infection is an urgent global public health priority. Metal-phenolic networks (MPNs) receive widespread attention in antimicrobial infections due to their facile synthesis process, excellent biocompatibility, and excellent… read more here.
Keywords: poly tannic; dually crosslinked; copper poly; tannic acid ... See more keywords
Application of a validated HPLC-PDA method for the determination of melatonin content and its release from poly(lactic acid) nanoparticles
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Pharmaceutical Analysis"
DOI: 10.1016/j.jpha.2017.05.007
Abstract: Melatonin is a natural hormone and with the advancement of age its production declines and thereby may result in some neurological disorders. Exogenous administration of melatonin has been suggested as a neuroprotective agent. Due to… read more here.
Keywords: poly lactic; acid nanoparticles; pda; method ... See more keywords
Synthesis of polyglycerol-citric acid nanoparticles as biocompatible vectors for biomedical applications
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Molecular Liquids"
DOI: 10.1016/j.molliq.2017.06.087
Abstract: Abstract Citric acid and glycerol play an important role in the food and drug industries. In this work, we present for the first time a facile and gram scale method for the preparation of polyglycerol-citric… read more here.
Keywords: citric acid; polyglycerol citric; acid nanoparticles; acid ... See more keywords
Development of Poly(lipoic acid) Nanoparticles with Improved Oral Bioavailability and Hepatoprotective Effects of Quercetin.
Sign Up to like & getrecommendations! Published in 2022 at "Molecular pharmaceutics"
DOI: 10.1021/acs.molpharmaceut.2c00009
Abstract: Quercetin (QUE)-loaded poly(lipoic acid) nanoparticles (QUE/pLA) were developed to improve chemical stability in the gastrointestinal (GI) tract, oral bioavailability (BA), and pharmacological properties of QUE. QUE/pLA was prepared by emulsion solvent evaporation with ultrasonication followed… read more here.
Keywords: lipoic acid; que; que pla; poly lipoic ... See more keywords
Polyethylenimine-Spherical Nucleic Acid Nanoparticles against Gli1 Reduce the Chemoresistance and Stemness of Glioblastoma Cells.
Sign Up to like & getrecommendations! Published in 2018 at "Molecular pharmaceutics"
DOI: 10.1021/acs.molpharmaceut.8b00707
Abstract: Glioblastoma (GBM) is the most common and lethal primary brain tumor in adults, with nearly 100% of patients ultimately succumbing to the disease. Median patient survival is 15 months, and no standard of care currently… read more here.
Keywords: nucleic acid; spherical nucleic; gli1 reduce; acid nanoparticles ... See more keywords
Structure and Composition Define Immunorecognition of Nucleic Acid Nanoparticles.
Sign Up to like & getrecommendations! Published in 2018 at "Nano letters"
DOI: 10.1021/acs.nanolett.8b01283
Abstract: Nucleic acid nanoparticles (NANPs) have evolved as a new class of therapeutics with the potential to detect and treat diseases. Despite tremendous advancements in NANP development, their immunotoxicity, one of the major impediments in clinical… read more here.
Keywords: acid nanoparticles; composition define; structure composition; define immunorecognition ... See more keywords
Charge Detection Mass Spectrometry Enables Molecular Characterization of Nucleic Acid Nanoparticles.
Sign Up to like & getrecommendations! Published in 2024 at "ACS nano"
DOI: 10.1021/acsnano.4c06313
Abstract: Nucleic acid nanoparticles (NANPs) are increasingly used in preclinical investigations as delivery vectors. Tools that can characterize assembly and assess quality will accelerate their development and clinical translation. Standard techniques used to characterize NANPs, like… read more here.
Keywords: nucleic acid; acid nanoparticles; charge detection; mass ... See more keywords
Chemical Composition and Backbone Modifications Define Deformability of Nucleic Acid Nanoparticles
Sign Up to like & getrecommendations! Published in 2025 at "ACS Nano"
DOI: 10.1021/acsnano.5c04293
Abstract: Nucleic acid nanoparticles (NANPs), composed of short oligonucleotides assembled into specific architectures, are emerging as a programmable platform for the regulated drug delivery of various therapeutic agents. Here, we use a nanopore “clamp” to investigate… read more here.
Keywords: nucleic acid; acid nanoparticles; deformability; rna ... See more keywords
The Application of Light-Assisted Drying to the Thermal Stabilization of Nucleic Acid Nanoparticles.
Sign Up to like & getrecommendations! Published in 2022 at "Biopreservation and biobanking"
DOI: 10.1089/bio.2022.0035
Abstract: Background: Cold-chain storage can be challenging and expensive for the transportation and storage of biologics, especially in low-resource settings. Nucleic acid nanoparticles (NANPs) are an example of new biological products that require refrigerated storage. Light-assisted… read more here.
Keywords: nucleic acid; light assisted; acid nanoparticles; assisted drying ... See more keywords
Chitosan-fulvic acid nanoparticles enhance drought tolerance in maize via antioxidant defense and transcriptional reprogramming.
Sign Up to like & getrecommendations! Published in 2024 at "Physiologia plantarum"
DOI: 10.1111/ppl.14455
Abstract: Nanoparticles are promising alternatives to synthetic fertilizers in the context of climate change and sustainable agriculture. Maize plants were grown under gradient concentrations (50 μM, 100 μM, 200 μM, 500 μM, and 1 mM) of chitosan (Ch), fulvic acid (FA)… read more here.
Keywords: acid nanoparticles; drought tolerance; fulvic acid; maize ... See more keywords
Co-Encapsulation of Violacein and Iron Oxide in Poly(lactic acid) Nanoparticles for Simultaneous Antibacterial and Anticancer Applications.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of biomedical nanotechnology"
DOI: 10.1166/jbn.2022.3305
Abstract: To date, the possibility of drug-resistant bacterial infections in hospitals and intensive care units comprises a significant concern especially for immunocompromised cancer patients. In the current study, violacein and superparamagnetic iron oxide nanoparticles were co-encapsulated… read more here.
Keywords: acid nanoparticles; anticancer; cancer; iron oxide ... See more keywords