Critical review of nucleic acid nanotechnology to identify gaps and inform a strategy for accelerated clinical translation.
Sign Up to like & getrecommendations! Published in 2021 at "Advanced drug delivery reviews"
DOI: 10.1016/j.addr.2021.114081
Abstract: With numerous recent advances, the field of therapeutic nucleic acid nanotechnology is now poised for clinical translation supported by several examples of FDA-approved nucleic acid nanoformulations including two recent mRNA-based COVID-19 vaccines. Within this rapidly… read more here.
Keywords: clinical translation; acid nanotechnology; nanotechnology; nucleic acid ... See more keywords
Synthesizing the biochemical and semiconductor worlds: the future of nucleic acid nanotechnology.
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DOI: 10.1039/d2nr04040a
Abstract: Since its inception nearly 40 years ago [Kallenbach, et al., Nature, 1983, 305, 829; N. C. Seeman, J. Theoretical Biology, 1982, 99, 237], Nucleic Acid Nanotechnology (NAN) has matured and is beginning to find commercial… read more here.
Keywords: nanotechnology; acid nanotechnology; semiconductor; nucleic acid ... See more keywords
Nucleic Acid Nanotechnology for Diagnostics and Therapeutics in Acute Kidney Injury
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DOI: 10.3390/ijms23063093
Abstract: Acute kidney injury (AKI) has impacted a heavy burden on global healthcare system with a high morbidity and mortality in both hospitalized and critically ill patients. However, there are still some shortcomings in clinical approaches… read more here.
Keywords: nanotechnology; acute kidney; acid nanotechnology; kidney injury ... See more keywords