Tannic acid as a natural antioxidant compound: Discovery of a potent metabolic enzyme inhibitor for a new therapeutic approach in diabetes and Alzheimer's disease
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.22340
Abstract: Multiple studies have been recorded on the synthesis and design of multi‐aim anti‐Alzheimer molecules. Using dual butyrylcholinesterase/acetylcholinesterase inhibitor molecules has attracted more interest in the therapy for Alzheimer's disease. In this study, a tannic acid… read more here.
Keywords: inhibitor; tannic acid; alzheimer disease; compound ... See more keywords
Betulinic acid: A natural promising anticancer drug, current situation, and future perspectives
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.23206
Abstract: Natural products serve as the single most productive source for the discovery of drugs and pharmaceutical leads. Among the various chemicals derived from microbes, plants, and animals, phytochemicals have emerged as potential candidates for the… read more here.
Keywords: anticancer drug; natural promising; drug current; promising anticancer ... See more keywords
α-d-Galacturonic Acid as Natural Ligand for Selective Copper-Catalyzed N-Arylation of N-Containing Heterocycles
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DOI: 10.1055/s-0039-1690226
Abstract: The first application of α-d-galacturonic acid hydrate (GalA) is reported here, as a potential O-donor ligand. The C–N couplings of N-heterocycles with aryl halides or arylboronic acids could be readily conducted and exhibited good functional… read more here.
Keywords: selective copper; natural ligand; acid natural; galacturonic acid ... See more keywords
Gallic Acid: A Natural Phenolic Compound Exerting Antitumoral Activities in Colorectal Cancer via Interaction with G-Quadruplexes
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DOI: 10.3390/cancers14112648
Abstract: Simple Summary Gallic acid, a natural phenolic compound in diet, interacts with DNA G-quadruplexes both in vitro and in vivo. In particular, gallic acid targets G-quadruplexes in ribosomal DNA and CMYC oncogene, affecting gene expression.… read more here.
Keywords: natural phenolic; compound; gallic acid; colorectal cancer ... See more keywords
Recent Developments in the Functionalization of Betulinic Acid and Its Natural Analogues: A Route to New Bioactive Compounds
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DOI: 10.3390/molecules24020355
Abstract: Betulinic acid (BA) and its natural analogues betulin (BN), betulonic (BoA), and 23-hydroxybetulinic (HBA) acids are lupane-type pentacyclic triterpenoids. They are present in many plants and display important biological activities. This review focuses on the… read more here.
Keywords: recent developments; developments functionalization; betulinic acid; natural analogues ... See more keywords
Ferulic Acid: A Natural Phenol That Inhibits Neoplastic Events through Modulation of Oncogenic Signaling
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DOI: 10.3390/molecules27217653
Abstract: Despite the immense therapeutic advances in the field of health sciences, cancer is still to be found among the global leading causes of morbidity and mortality. Ethnomedicinally, natural bioactive compounds isolated from various plant sources… read more here.
Keywords: neoplastic events; natural phenol; inhibits neoplastic; phenol inhibits ... See more keywords
A Concise Profile of Gallic Acid—From Its Natural Sources through Biological Properties and Chemical Methods of Determination
Sign Up to like & getrecommendations! Published in 2023 at "Molecules"
DOI: 10.3390/molecules28031186
Abstract: Nature is a valuable source of anti-oxidants that have a health-promoting effect by inhibiting various undesirable changes leading to cell degradation and, consequently, potential disease ailments. One of them is gallic acid which has been… read more here.
Keywords: concise profile; gallic acid; profile gallic; determination ... See more keywords