Lactobacillus casei YRL577 ameliorates markers of non-alcoholic fatty liver and alters expression of genes within the intestinal bile acid pathway
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DOI: 10.1017/s0007114520003001
Abstract: Abstract Non-alcoholic fatty liver disease (NAFLD) has become the main cause of end-stage liver disease. Probiotics have the potential effect of alleviating NAFLD. The aim of this study was to explore functional probiotics and their… read more here.
Keywords: yrl577; casei yrl577; intestinal bile; bile acid ... See more keywords
Uric acid pathway activation during Respiratory virus infection promotes Th2 immune responses via innate cytokine production and ILC2 accumulation
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DOI: 10.1038/s41385-020-0264-z
Abstract: Respiratory syncytial virus (RSV) infects a majority of infants and can cause severe disease leading to increased risk to develop asthma later in life. In the present studies we detected high levels of uric acid… read more here.
Keywords: uric acid; infection; rsv; acid pathway ... See more keywords
A common polymorphism in the retinoic acid pathway modifies adrenocortical carcinoma age-dependent incidence
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DOI: 10.1038/s41416-020-0764-3
Abstract: Background Genome-wide association studies (GWASs) have enriched the fields of genomics and drug development. Adrenocortical carcinoma (ACC) is a rare cancer with a bimodal age distribution and inadequate treatment options. Paediatric ACC is frequently associated… read more here.
Keywords: retinoic acid; age; acid pathway; adrenocortical carcinoma ... See more keywords
Anisomycin has a potential toxicity of promoting cuproptosis in human ovarian cancer stem cells by attenuating YY1/lipoic acid pathway activation
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DOI: 10.7150/jca.77445
Abstract: Ovarian cancer is a highly malignant gynecologic tumor that seriously endangers women's health. We previously demonstrated that anisomycin significantly inhibited the activity of ovarian cancer stem cells (OCSCs) in vitro and in vivo. In the… read more here.
Keywords: cuproptosis; cancer stem; ovarian cancer; acid pathway ... See more keywords