Cascading Effects of Plant Hormone-induced Trait Shifts in Alnus rubra on Aquatic and Terrestrial Ecosystem Function
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DOI: 10.1007/s10886-025-01644-9
Abstract: While intraspecific trait variation can regulate ecosystem functions, there is limited understanding of whether this variation caused by inducible phenotypic shifts, as opposed to genetic hardwiring, can have such effects. Leveraging the complex inducible defense… read more here.
Keywords: plant; plant hormone; acid pathway; aquatic terrestrial ... See more keywords
Lactobacillus casei YRL577 ameliorates markers of non-alcoholic fatty liver and alters expression of genes within the intestinal bile acid pathway
Sign Up to like & getrecommendations! Published in 2020 at "British Journal of Nutrition"
DOI: 10.1017/s0007114520003001
Abstract: Abstract Non-alcoholic fatty liver disease (NAFLD) has become the main cause of end-stage liver disease. Probiotics have the potential effect of alleviating NAFLD. The aim of this study was to explore functional probiotics and their… read more here.
Keywords: yrl577; casei yrl577; intestinal bile; bile acid ... See more keywords
Amyloidogenic Propensity of Metabolites in the Uric Acid Pathway and Urea Cycle Critically Impacts the Etiology of Metabolic Disorders.
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DOI: 10.1021/acschemneuro.3c00563
Abstract: Novel insights into the etiology of metabolic disorders have recently been uncovered through the study of metabolite amyloids. In particular, inborn errors of metabolism (IEMs), including gout, Lesch-Nyhan syndrome (LNS), xanthinuria, citrullinemia, and hyperornithinemia-hyperammonemia-homocitrullinuria (HHH)… read more here.
Keywords: etiology; acid pathway; metabolic disorders; urea cycle ... See more keywords
Uric acid pathway activation during Respiratory virus infection promotes Th2 immune responses via innate cytokine production and ILC2 accumulation
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DOI: 10.1038/s41385-020-0264-z
Abstract: Respiratory syncytial virus (RSV) infects a majority of infants and can cause severe disease leading to increased risk to develop asthma later in life. In the present studies we detected high levels of uric acid… read more here.
Keywords: uric acid; infection; rsv; acid pathway ... See more keywords
A common polymorphism in the retinoic acid pathway modifies adrenocortical carcinoma age-dependent incidence
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DOI: 10.1038/s41416-020-0764-3
Abstract: Background Genome-wide association studies (GWASs) have enriched the fields of genomics and drug development. Adrenocortical carcinoma (ACC) is a rare cancer with a bimodal age distribution and inadequate treatment options. Paediatric ACC is frequently associated… read more here.
Keywords: retinoic acid; age; acid pathway; adrenocortical carcinoma ... See more keywords
Anisomycin has a potential toxicity of promoting cuproptosis in human ovarian cancer stem cells by attenuating YY1/lipoic acid pathway activation
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Cancer"
DOI: 10.7150/jca.77445
Abstract: Ovarian cancer is a highly malignant gynecologic tumor that seriously endangers women's health. We previously demonstrated that anisomycin significantly inhibited the activity of ovarian cancer stem cells (OCSCs) in vitro and in vivo. In the… read more here.
Keywords: cuproptosis; cancer stem; ovarian cancer; acid pathway ... See more keywords