Synthesis and antimicrobial activity of amino acid and peptide derivatives of mycophenolic acid
Sign Up to like & getrecommendations! Published in 2018 at "European Journal of Medicinal Chemistry"
DOI: 10.1016/j.ejmech.2017.11.094
Abstract: Abstract The series of 16 novel amino acid and peptide mycophenolic acid (MPA) derivatives was obtained as potential antibacterial agents. Coupling of MPA with respective amines was optimized with condensing reagents such as EDCI/DMAP and… read more here.
Keywords: amino; amino acid; acid peptide; mycophenolic acid ... See more keywords
Immunosuppressive properties of amino acid and peptide derivatives of mycophenolic acid.
Sign Up to like & getrecommendations! Published in 2020 at "European journal of medicinal chemistry"
DOI: 10.1016/j.ejmech.2020.112091
Abstract: Mycophenolic acid (MPA) was coupled with amino acids and biologically active peptides including derivatives of tuftsin to modify its immunosuppressive properties. Both amino acid unit in the case of simple MPA amides and modifications within… read more here.
Keywords: immunosuppressive properties; amino acid; acid peptide; mycophenolic acid ... See more keywords
Stability improvement of natural food colors: Impact of amino acid and peptide addition on anthocyanin stability in model beverages.
Sign Up to like & getrecommendations! Published in 2017 at "Food chemistry"
DOI: 10.1016/j.foodchem.2016.09.087
Abstract: Anthocyanins are prone to chemical degradation and color fading in the presence of vitamin C. The potential of three amino acids (l-phenylalanine, l-tyrosine, l-tryptophan) and a polypeptide (ε-poly-l-lysine) in prolonging the color stability of purple… read more here.
Keywords: color; amino acid; addition; acid peptide ... See more keywords
Deciphering the Role of Intramolecular Networking in Cholic Acid-Peptide Conjugates on the Lipopolysaccharide Surface in Combating Gram-Negative Bacterial Infections.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of medicinal chemistry"
DOI: 10.1021/acs.jmedchem.8b01357
Abstract: The presence of lipopolysaccharide and emergence of drug resistance make the treatment of Gram-negative bacterial infections highly challenging. Herein, we present the synthesis and antibacterial activities of cholic acid-peptide conjugates (CAPs), demonstrating that valine-glycine dipeptide-derived… read more here.
Keywords: peptide conjugates; gram negative; acid peptide; cholic acid ... See more keywords
Dynamic exchange controls the assembly structure of nucleic-acid-peptide chimeras.
Sign Up to like & getrecommendations! Published in 2023 at "Soft matter"
DOI: 10.1039/d2sm01528e
Abstract: Recent attempts to develop the next generation of functional biomaterials focus on systems chemistry approaches exploiting dynamic networks of hybrid molecules. This task is often found challenging, but we herein present ways for profiting from… read more here.
Keywords: exchange controls; chemistry; dynamic exchange; peptide ... See more keywords