A caffeic acid phenethyl ester analog inhibits the proliferation of nasopharyngeal carcinoma cells via targeting epidermal growth factor receptor
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.22491
Abstract: A previous study reported that compound 5A, a caffeic acid phenethyl ester (CAPE) analog, exhibited obvious neuroprotective activity, in particular, compound 5A possessed higher stability and membrane permeability than CAPE. CAPE displays antitumour function; therefore,… read more here.
Keywords: caffeic acid; phenethyl ester; proliferation; analog ... See more keywords
Caffeic acid phenethyl ester: A review on its pharmacological importance, and its association with free radicals, COVID‐19, and radiotherapy
Sign Up to like & getrecommendations! Published in 2022 at "Phytotherapy Research"
DOI: 10.1002/ptr.7707
Abstract: Caffeic acid phenethyl ester (CAPE), a main active component of propolis and a flavonoid, is one of the natural products that has attracted attention in recent years. CAPE, which has many properties such as anti‐cancer,… read more here.
Keywords: acid phenethyl; phenethyl ester; cape; caffeic acid ... See more keywords
Recent progresses in the pharmacological activities of caffeic acid phenethyl ester.
Sign Up to like & getrecommendations! Published in 2021 at "Naunyn-Schmiedeberg's archives of pharmacology"
DOI: 10.1007/s00210-021-02054-w
Abstract: The past decades have seen a growing interest in natural products. Caffeic acid phenethyl ester (CAPE), a flavonoid isolated from honeybee propolis, has shown multiple pharmacological potentials, including anti-cancer, anti-inflammatory, antioxidant, antibacterial, antifungal, and protective… read more here.
Keywords: caffeic acid; recent progresses; progresses pharmacological; phenethyl ester ... See more keywords
Antiradical properties of curcumin, caffeic acid phenethyl ester, and chicoric acid: a DFT study
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Molecular Modeling"
DOI: 10.1007/s00894-022-05056-4
Abstract: The antiradical properties and possible mechanisms of action of the tautomers of curcumin, caffeic acid phenethyl ester (CAPE), and chicoric acid (CA) have been studied within density functional theory (DFT). We calculated global chemical reactivity… read more here.
Keywords: dft; acid phenethyl; caffeic acid; curcumin caffeic ... See more keywords
Caffeic Acid Phenethyl Ester (CAPE) Protects PC12 Cells from Cisplatin-Induced Neurotoxicity by Activating the NGF-Signaling Pathway
Sign Up to like & getrecommendations! Published in 2017 at "Neurotoxicity Research"
DOI: 10.1007/s12640-017-9849-z
Abstract: Cisplatin is a highly effective chemotherapeutic drug that is toxic to the peripheral nervous system. Findings suggest that axons are early targets of the neurotoxicity of cisplatin. Although many compounds have been reported as neuroprotective,… read more here.
Keywords: caffeic acid; cisplatin; cape; neurotoxicity ... See more keywords
Discovery of caffeic acid phenethyl ester derivatives as novel myeloid differentiation protein 2 inhibitors for treatment of acute lung injury.
Sign Up to like & getrecommendations! Published in 2018 at "European journal of medicinal chemistry"
DOI: 10.1016/j.ejmech.2017.11.066
Abstract: Myeloid differentiation protein 2 (MD2) is an essential molecule which recognizes lipopolysaccharide (LPS), leading to initiation of inflammation through the activation of Toll-like receptor 4 (TLR4) signaling. Caffeic acid phenethyl ester (CAPE) from propolis of… read more here.
Keywords: caffeic acid; differentiation protein; phenethyl ester; myeloid differentiation ... See more keywords
Antibacterial and antioxidant electrospun materials from poly(3‐hydroxybutyrate) and polyvinylpyrrolidone containing caffeic acid phenethyl ester – “in” and “on” strategies for enhanced solubility
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Pharmaceutics"
DOI: 10.1016/j.ijpharm.2018.05.013
Abstract: ABSTRACT Caffeic acid phenethyl ester (CAPE) possesses a set of valuable biological properties: antioxidant, antibacterial, antitumor, anti‐inflammatory, antiviral, etc. However, CAPE is poorly soluble in aqueous environment which is limiting its possible therapeutic applications. In… read more here.
Keywords: caffeic acid; phenethyl ester; poly hydroxybutyrate; cape ... See more keywords
Analysis of the Effect of N555 Mutations on the Product Specificity of Dextransucrase Using Caffeic Acid Phenethyl Ester as an Acceptor Substrate.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.1c00822
Abstract: Bioglycosylation is an efficient strategy to improve biological activities and physicochemical properties of natural compounds to develop structural modifications of drugs. In this study, an N555 residue was identified as a candidate for site-directed mutagenesis… read more here.
Keywords: caffeic acid; acceptor substrate; phenethyl ester; acid phenethyl ... See more keywords
Caffeic acid phenethyl ester protects against oxidative stress and dampens inflammation via heme oxygenase 1
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Oral Science"
DOI: 10.1038/s41368-018-0039-5
Abstract: Periodontal disease is associated with chronic oxidative stress and inflammation. Caffeic acid phenethyl ester (CAPE), which is a potent inducer of heme oxygenase 1 (HO1), is a central active component of propolis, and the application of… read more here.
Keywords: caffeic acid; phenethyl ester; inflammation; cape ... See more keywords
Co-delivery of quercetin and caffeic-acid phenethyl ester by polymeric nanoparticles for improved antitumor efficacy in colon cancer cells
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Microencapsulation"
DOI: 10.1080/02652048.2021.1948623
Abstract: Abstract Aim This study aimed to synthesise quercetin- caffeic-acid phenethyl ester (CAPE)-co-loaded poly(lactic-co-glycolic-acid) (PLGA) nanoparticles (QuCaNP) and investigate their anti-cancer activity on human colorectal carcinoma HT-29 cells. Methods QuCaNPs were synthesised using single-emulsion (o/w) solvent… read more here.
Keywords: caffeic acid; acid phenethyl; quercetin caffeic; cancer ... See more keywords
Antifilarial activity of caffeic acid phenethyl ester on Brugia pahangi in vitro and in vivo
Sign Up to like & getrecommendations! Published in 2017 at "Pathogens and Global Health"
DOI: 10.1080/20477724.2017.1380946
Abstract: Abstract Lymphatic filariasis (LF) is a vector borne disease caused by parasitic worms such as Wuchereria bancrofti, Brugia malayi and B. timori, which are transmitted by mosquitoes. Current therapeutics to treat LF are mainly microfilarcidal,… read more here.
Keywords: caffeic acid; phenethyl ester; pahangi; cape ... See more keywords