Avian and human influenza virus compatible sialic acid receptors in little brown bats
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-00793-6
Abstract: Influenza A viruses (IAVs) continue to threaten animal and human health globally. Bats are asymptomatic reservoirs for many zoonotic viruses. Recent reports of two novel IAVs in fruit bats and serological evidence of avian influenza… read more here.
Keywords: avian human; influenza; receptors little; influenza virus ... See more keywords
Structural basis for DNA recognition and allosteric control of the retinoic acid receptors RAR–RXR
Sign Up to like & getrecommendations! Published in 2020 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkaa697
Abstract: Abstract Retinoic acid receptors (RARs) as a functional heterodimer with retinoid X receptors (RXRs), bind a diverse series of RA-response elements (RAREs) in regulated genes. Among them, the non-canonical DR0 elements are bound by RXR–RAR… read more here.
Keywords: retinoic acid; acid receptors; rxr rar; dna ... See more keywords
Bile acid receptors and the kidney
Sign Up to like & getrecommendations! Published in 2018 at "Current Opinion in Nephrology and Hypertension"
DOI: 10.1097/mnh.0000000000000374
Abstract: Purpose of review Bile acids act as activating signals of endogenous renal receptors: the nuclear receptor farnesoid X receptor (FXR) and the membrane-bound G protein-coupled bile acid receptor 1 (GPBAR1, also known as TGR5). In… read more here.
Keywords: receptors kidney; biology; receptor; bile acid ... See more keywords
Arabidopsis ALIX Regulates Stomatal Aperture and Turnover of Abscisic Acid Receptors
Sign Up to like & getrecommendations! Published in 2019 at "Plant Cell"
DOI: 10.1105/tpc.19.00399
Abstract: ALIX mediates endosomal trafficking and turnover of abscisic acid receptors through the ESCRT/MVB pathway, modulating abscisic acid–mediated inhibition of plant growth and stomatal aperture. The plant endosomal trafficking pathway controls the abundance of membrane-associated soluble… read more here.
Keywords: abscisic acid; turnover abscisic; stomatal aperture; alix ... See more keywords
Placental expression of lysophosphatidic acid receptors in normal pregnancy and preeclampsia
Sign Up to like & getrecommendations! Published in 2019 at "American Journal of Reproductive Immunology"
DOI: 10.1111/aji.13176
Abstract: Recent advances in lipid research have revealed that impairments in lipid mediator signaling can be involved in the pathoetiology of a variety of diseases. We previously reported aberrant expression of autotaxin, a key enzyme for… read more here.
Keywords: placental expression; expression lysophosphatidic; expression; receptors normal ... See more keywords
Free fatty acid receptors, FFAR1 and FFAR4, are novel bronchodilator targets in mouse and human precision-cut lung slices
Sign Up to like & getrecommendations! Published in 2018 at "European Respiratory Journal"
DOI: 10.1183/13993003.congress-2018.pa5259
Abstract: Background: Alternative dilator targets need to be identified for severe asthma, as excessive use of β2-adrenoceptor agonists causes desensitization and loss of efficacy. Free fatty acid receptors, FFAR1 and FFAR4, are highly expressed in mouse… read more here.
Keywords: fatty acid; free fatty; ffar1 ffar4; mouse human ... See more keywords
Retinoic acid receptors at 35 years.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of molecular endocrinology"
DOI: 10.1530/jme-22-0097
Abstract: For almost a century, vitamin A has been known as a nutrient critical for normal development, differentiation, and homeostasis; accordingly, there has been much interest in understanding its mechanism of action. This review is about… read more here.
Keywords: receptors years; retinoic acid; acid receptors; endocrinology ... See more keywords
Free Fatty Acid Receptors (FFARs): Emerging Therapeutic Targets for the Management of Diabetes Mellitus.
Sign Up to like & getrecommendations! Published in 2022 at "Current medicinal chemistry"
DOI: 10.2174/0929867329666220927113614
Abstract: Free fatty acids (FFAs) present in our dietary fats not only act as vital nutrients but also function as signalling molecules and modulate key biological functions through their active involvement in a multitude of energy… read more here.
Keywords: free fatty; acid receptors; diabetes mellitus; fatty acid ... See more keywords
Free Fatty Acid Receptors as Mediators and Therapeutic Targets in Liver Disease
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2021.656441
Abstract: Free fatty acid receptors (FFARs) are a class of G protein-coupled receptors (GPCRs) that have wide-ranging effects on human physiology. The four well-characterized FFARs are FFAR1/GPR40, FFAR2/GPR43, FFAR3/GPR41, and FFAR4/GPR120. Short-chain ( read more here.
Keywords: fatty acid; free fatty; physiology; liver disease ... See more keywords
Liver Steatosis and Steatohepatitis Alter Bile Acid Receptors in Brain and Induce Neuroinflammation: A Contribution of Circulating Bile Acids and Blood-Brain Barrier
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms232214254
Abstract: A tight relationship between gut-liver diseases and brain functions has recently emerged. Bile acid (BA) receptors, bacterial-derived molecules and the blood-brain barrier (BBB) play key roles in this association. This study was aimed to evaluate… read more here.
Keywords: blood brain; brain barrier; brain; acid receptors ... See more keywords