Liver and/or kidney transplantation in amino and organic acid‐related inborn errors of metabolism: An overview on European data
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Inherited Metabolic Disease"
DOI: 10.1002/jimd.12318
Abstract: This study provides a general overview on liver and/or kidney transplantation in patients with an amino and organic acid‐related disorder (AOA) with the aim to investigate patient characteristics and global outcome in Europe. This study… read more here.
Keywords: liver kidney; kidney transplantation; amino organic; organic acid ... See more keywords
Synthesis of A-9758, an Inverse Agonist of Retinoic Acid-Related Orphan Receptor γt
Sign Up to like & getrecommendations! Published in 2022 at "ACS Omega"
DOI: 10.1021/acsomega.2c06060
Abstract: A-9758 is an inverse agonist of retinoic acid-related orphan receptor γt with well-characterized in vitro and in vivo anti-inflammatory activity. A chromatography-free decagram-scale synthesis of this compound was developed to support pre-clinical research activities. This… read more here.
Keywords: acid related; agonist retinoic; acid; 9758 inverse ... See more keywords
Crystal structures of N6-modified-amino acid related nucleobase analogs (II): hybrid adenine-β-alanine and adenine-GABA molecules
Sign Up to like & getrecommendations! Published in 2019 at "New Journal of Chemistry"
DOI: 10.1039/c9nj02279a
Abstract: H-Bonding networks and anion–π interactions in the crystal structures of N6-modified-amino acid adenine analogs are investigated using X-ray crystallography and DFT calculations. read more here.
Keywords: crystal structures; modified amino; structures modified; adenine ... See more keywords
Synthesis of some novel orsellinates and lecanoric acid related depsides as α-glucosidase inhibitors
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Asian Natural Products Research"
DOI: 10.1080/10286020.2018.1490274
Abstract: Abstract Sixteen novel orsellinic esters (6a-l, 7a-d) along with four lecanoric acid related depsides (3a-c, 4) were synthesized and confirmed their structures by spectroscopic data (1H, 13C & HRMS). The synthesized compounds were evaluated for… read more here.
Keywords: synthesis novel; lecanoric acid; novel orsellinates; acid related ... See more keywords
Vonoprazan fumarate for the management of acid-related diseases
Sign Up to like & getrecommendations! Published in 2017 at "Expert Opinion on Pharmacotherapy"
DOI: 10.1080/14656566.2017.1346087
Abstract: ABSTRACT Introduction: Proton pump inhibitors (PPIs) display a number of limitations and unmet clinical needs that have prompted the development of novel drugs to improve the outcomes of acid-related diseases, including the eradication of H.… read more here.
Keywords: vonoprazan fumarate; fumarate management; related diseases; acid related ... See more keywords
A safety review of proton pump inhibitors to treat acid-related digestive diseases
Sign Up to like & getrecommendations! Published in 2018 at "Expert Opinion on Drug Safety"
DOI: 10.1080/14740338.2018.1497155
Abstract: ABSTRACT Introduction: Proton pump inhibitors (PPIs) have become the first choice medical treatment of acid-related disease and, as with any pharmacological agent, they have been reported to be associated with some adverse events mainly linked… read more here.
Keywords: proton pump; pump inhibitors; safety; acid related ... See more keywords
The risk of pulmonary adverse drug reactions of rebamipide and other drugs for acid‐related diseases: An analysis of the national pharmacovigilance database in South Korea
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Digestive Diseases"
DOI: 10.1111/1751-2980.13075
Abstract: The objective of this case/non‐case study was to detect rebamipide‐related pulmonary adverse events (AE) compared with other drugs for acid‐related disorders based on population‐level data. read more here.
Keywords: drug reactions; pulmonary adverse; drugs acid; adverse drug ... See more keywords
Pharmacological Approach to Gastric Acid Suppression: Past, Present, and Future
Sign Up to like & getrecommendations! Published in 2019 at "Digestive Diseases"
DOI: 10.1159/000505204
Abstract: Less than 2 centuries have elapsed since the identification of hydrochloric acid in the stomach. The clarification of the molecular mechanisms allowed the effective therapeutic suppression of gastric acid secretion. The spectacular advances in the… read more here.
Keywords: suppression; related disorders; acid related; therapy ... See more keywords
Melatonin Regulates lncRNA NEAT1/miR-138-5p/HIF-1α Axis through MOV10 to Affect Acid-Related Esophageal Epithelial Cell Pyroptosis.
Sign Up to like & getrecommendations! Published in 2023 at "Pharmacology"
DOI: 10.1159/000530090
Abstract: INTRODUCTION Acid-related inflammatory damage to the esophageal epithelium is a key component in the development of gastroesophageal reflux disease. Melatonin (MT) is considered as a potential therapeutic agent, but its molecular mechanism is unknown. METHODS… read more here.
Keywords: acid related; lncrna neat1; mov10; mir 138 ... See more keywords
Accumulation of Salicylic Acid and Related Metabolites in Selaginella moellendorffii
Sign Up to like & getrecommendations! Published in 2022 at "Plants"
DOI: 10.3390/plants11030461
Abstract: Salicylic acid (SA) is a phytohormone that plays manifold roles in plant growth, defense, and other aspects of plant physiology. The concentration of free SA in plants is fine-tuned by a variety of structural modifications.… read more here.
Keywords: acid related; metabolites selaginella; salicylic acid; selaginella moellendorffii ... See more keywords