Acid-Responsive H2 -Releasing 2D MgB2 Nanosheet for Therapeutic Synergy and Side Effect Attenuation of Gastric Cancer Chemotherapy.
Sign Up to like & getrecommendations! Published in 2019 at "Advanced healthcare materials"
DOI: 10.1002/adhm.201900157
Abstract: The hydrogen molecule is recognized as a high potential to attenuate toxic side effects of chemotherapy and also enhance chemotherapeutic efficacy, and the development of a novel hydrogen-generating prodrug for facile, safe, and efficient hydrogen… read more here.
Keywords: hydrogen; gastric cancer; synergy side; side ... See more keywords
One‐Step Synthesis of Hydrogel Adhesive with Acid‐Responsive Tannin Release for Diabetic Oral Mucosa Defects Healing
Sign Up to like & getrecommendations! Published in 2024 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202303252
Abstract: The complex preparation, weak wet tissue adhesion, and limited biological activity of traditional oral wound dressings usually impede their efficient treatment and healing for diabetic oral mucosal defects. To overcome these problems, a novel hydrogel… read more here.
Keywords: cft hydrogel; hydrogel; one step; hydrogel adhesive ... See more keywords
Acid‐Responsive Bacteria‐Targeted Zinc‐Porphyrin Based Sonosensitizer with Enhancing Antibacterial Efficacy and Biofilm Eradication for Infected Wounds Healing
Sign Up to like & getrecommendations! Published in 2025 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202404643
Abstract: Diseases caused by bacterial infections place a significant burden on global public health. Sonodynamic therapy (SDT), as an emerging antibacterial treatment, faces clinical challenges due to the non‐polar nature of most sonosensitizers. To address this,… read more here.
Keywords: based sonosensitizer; acid responsive; infected wounds; porphyrin based ... See more keywords
Acid‐Responsive Inks via Shuttling in a Pseudorotaxane Complex
Sign Up to like & getrecommendations! Published in 2025 at "Chempluschem"
DOI: 10.1002/cplu.202500453
Abstract: Pseudorotaxanes are host‐guest complexes where a guest molecule threads through a ring‐shaped host via noncovalent interactions. If the guest has two recognition sites, the host can dynamically shuttle between them. These complexes enable stimulus‐responsive molecular… read more here.
Keywords: host; inks via; cbpqt4; acid responsive ... See more keywords
Design Synthesis, and Acid-Responsive Disassembly of Shell-Sheddable Block Copolymer Labeled with Benzaldehyde Acetal Junction.
Sign Up to like & getrecommendations! Published in 2024 at "Macromolecular rapid communications"
DOI: 10.1002/marc.202400097
Abstract: Smart nanoassemblies degradable through the cleavage of acid-labile linkages have attracted significant attention because of their biological relevance found in tumor tissues and cancer cells. Despite their high potential for tumor-targeting drug delivery exhibiting controlled/enhanced… read more here.
Keywords: junction; synthesis; block; shell sheddable ... See more keywords
Acid‐Responsive N‐Heteroacene‐Based Material Showing Multi‐Emission Colors
Sign Up to like & getrecommendations! Published in 2017 at "ChemistryOpen"
DOI: 10.1002/open.201700007
Abstract: Abstract An acid‐responsive N‐heteroacene‐based material has been prepared, which shows a blue emission color in a film. The protonation of this material in a thin film gives rise to remarkable changes in luminescent color compared… read more here.
Keywords: responsive heteroacene; material; heteroacene based; heteroacene ... See more keywords
Acid-Responsive Aggregated Gold Nanoparticles for Radiosensitization and Synergistic Chemoradiotherapy in the Treatment of Esophageal Cancer.
Sign Up to like & getrecommendations! Published in 2022 at "Small"
DOI: 10.1002/smll.202200115
Abstract: Radiotherapy and chemotherapy are limited by insufficient therapeutic efficacy of low-dose radiation and nonspecific drug biodistribution. Herein, an acid-responsive aggregated nanosystem (AuNPs-D-P-DA) loaded with doxorubicin (DOX) is designed for radiosensitization and synergistic chemoradiotherapy. In response… read more here.
Keywords: radiosensitization; responsive aggregated; aunps; acid responsive ... See more keywords
Acid-Responsive Disassembly of Nanomedicines for Extracellular Drug Delivery Reversing Glioblastoma Immunosuppressive Microenvironment by Targeting the Adenosine-A2AR Pathway.
Sign Up to like & getrecommendations! Published in 2025 at "Small"
DOI: 10.1002/smll.202411689
Abstract: The efficacy of checkpoint blockade immunotherapy for glioblastoma (GBM) is significantly influenced by the precise delivery of therapeutic agents that can penetrate the blood-brain barrier (BBB) and reprogram the tumor immune microenvironment. Conventional nanoscale carriers… read more here.
Keywords: extracellular drug; delivery; microenvironment; glioblastoma ... See more keywords
Acid-Responsive Multifunctional Zeolitic Imidazolate Framework-8 (ZIF-8) Nanocomposites for Tumor Chemo-Photothermal Synergistic Therapy.
Sign Up to like & getrecommendations! Published in 2022 at "Bioconjugate chemistry"
DOI: 10.1021/acs.bioconjchem.2c00246
Abstract: Camptothecin (CPT), a broad-spectrum anticancer drug, has been extensively used clinically. However, its hydrophobic properties seriously hinder its antitumor therapeutic effect. Herein, we synthesized acid-degradable Fe3O4@poly(vinylpyrrolidone) (Fe3O4@PVP)/gold nanoclusters@zeolitic imidazolate framework-8 composite nanoparticles (ZIF-8CNPs) via a… read more here.
Keywords: imidazolate framework; tumor; photothermal synergistic; zeolitic imidazolate ... See more keywords
Acid-Responsive Biocompatible Hydrogel Modulating Tumor DNA Self-Repair Collaborated with Chemotherapy for Boosting STING Pathway-Associated Immunotherapy.
Sign Up to like & getrecommendations! Published in 2025 at "Nano letters"
DOI: 10.1021/acs.nanolett.5c00358
Abstract: In this study, an acid-responsive hydrogel (ODCM@AZD) encapsulating doxorubicin (DOX), Mn2+, and AZD2281 is rationally engineered for synergistic chemo-immunotherapy. Notably, ODCM@AZD can be specifically degraded within the tumor microenvironment to release the loaded therapeutic agents.… read more here.
Keywords: hydrogel; immunotherapy; sting pathway; tumor ... See more keywords
Synthesis and Acid-Responsive Properties of a Highly Porous Vinylene-Linked Covalent Organic Framework.
Sign Up to like & getrecommendations! Published in 2021 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.1c01791
Abstract: The recently emerging vinylene-linked covalent organic frameworks (VCOFs) stand out from other COFs with exceptional chemical stability and favorable light-emitting properties, promising sensing applications for acids/bases or in strong acidic/basic conditions. Here we systematically investigated… read more here.
Keywords: vinylene; linked covalent; synthesis acid; vinylene linked ... See more keywords