Gambogic acid suppresses the pentose phosphate pathway by covalently inhibiting 6PGD protein in cancer cells.
Sign Up to like & getrecommendations! Published in 2022 at "Chemical communications"
DOI: 10.1039/d2cc03069a
Abstract: Whether or not the anticancer activity of gambogic acid is achieved via regulating the cellular metabolic process remains unclear. Here we report that gambogic acid suppresses the pentose phosphate pathway (PPP) by covalently inhibiting the… read more here.
Keywords: suppresses pentose; phosphate pathway; acid suppresses; pentose phosphate ... See more keywords
Anacardic Acid Suppresses Adipogenesis Through Inhibition of the Hsp90/Akt Signaling Pathway in 3T3-L1 Preadipocytes.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of medicinal food"
DOI: 10.1089/jmf.2020.4830
Abstract: Anacardic acid (AA), a major component of cashew nut shell liquid, has extensive bioactivities. However, little is known about its antiadipogenic properties or the mechanism that underpins them. The aim of this study was to… read more here.
Keywords: akt signaling; acid suppresses; suppresses adipogenesis; signaling pathway ... See more keywords
Ginkgolic Acid Suppresses Nasopharyngeal Carcinoma Growth by Inducing Apoptosis and Inhibiting AKT/NF-κB Signaling.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of medicinal food"
DOI: 10.1089/jmf.2021.k.0059
Abstract: Even though nasopharyngeal carcinoma (NPC) is not common worldwide, it is a major public health burden in endemic areas. Distant metastasis often leads to a poor prognosis for NPC; therefore, new and effective anticancer strategies… read more here.
Keywords: acid suppresses; carcinoma growth; apoptosis; ginkgolic acid ... See more keywords
Glycyrrhizic acid suppresses atopic dermatitis‐like symptoms by regulating the immune balance
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Cosmetic Dermatology"
DOI: 10.1111/jocd.15383
Abstract: Glycyrrhiza is one of the most widely used traditional Chinese medicines in China. Its main bioactive ingredient glycyrrhizic acid (GA) has the potential to be used as a treatment for atopic dermatitis (AD) because it… read more here.
Keywords: atopic dermatitis; suppresses atopic; glycyrrhizic acid; acid suppresses ... See more keywords
Chebulinic Acid Suppresses Adipogenesis in 3T3-L1 Preadipocytes by Inhibiting PPP1CB Activity
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23020865
Abstract: Depletion of protein phosphatase-1 catalytic subunit beta (PPP1CB), a serine/threonine protein phosphatase and potent adipogenic activator, suppresses the differentiation of 3T3-L1 preadipocytes into mature adipocytes. Therefore, PPP1CB is considered as a potential therapeutic target for… read more here.
Keywords: acid suppresses; 3t3 preadipocytes; ppp1cb; adipogenesis 3t3 ... See more keywords