Association of Gastric Acid Suppression With Recurrent Clostridium difficile Infection: A Systematic Review and Meta-analysis
Sign Up to like & getrecommendations! Published in 2017 at "JAMA Internal Medicine"
DOI: 10.1001/jamainternmed.2017.0212
Abstract: Importance Gastric acid suppression has been associated with an increased risk of primary Clostridium difficile infection (CDI), but the risk of recurrent CDI in patients taking gastric acid suppressant medications is unclear. Objective To perform… read more here.
Keywords: acid suppression; acid; recurrent cdi; gastric acid ... See more keywords
Potassium-competitive Acid Blockers: Current Clinical Use and Future Developments
Sign Up to like & getrecommendations! Published in 2024 at "Current Gastroenterology Reports"
DOI: 10.1007/s11894-024-00939-3
Abstract: Acid suppression with proton pump inhibitors (PPIs) represents the standard of care in the treatment of acid-related diseases. However, despite their effectiveness, PPIs display some intrinsic limitations, which underlie the unmet clinical needs that have… read more here.
Keywords: acid blockers; acid suppression; competitive acid; acid ... See more keywords
Optimization of acid suppression utilizing esophageal ambulatory pH monitoring: a single center retrospective review
Sign Up to like & getrecommendations! Published in 2025 at "Baylor University Medical Center Proceedings"
DOI: 10.1080/08998280.2025.2553073
Abstract: Abstract Background Ambulatory esophageal reflux monitoring allows for objective differentiation of pathologic reflux, reflux hypersensitivity, and functional heartburn. Defining a diagnosis as the etiology of symptoms allows for appropriate medication management, and specifically de-escalation of… read more here.
Keywords: reflux; review; acid suppression; monitoring ... See more keywords
Educational intervention can improve appropriateness of acid suppression therapy in hospitalized geriatric patients
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Community Hospital Internal Medicine Perspectives"
DOI: 10.1080/20009666.2019.1571881
Abstract: ABSTRACT Background: Inappropriate use of acid suppression (AST) therapy may lead to unnecessary harms, especially in the geriatric population. Despite this, AST remains one of the most commonly prescribed medications in the hospital. Therefore, we… read more here.
Keywords: suppression; acid suppression; educational intervention; suppression therapy ... See more keywords
Quality of life and gastric acid‐suppression medication 20 years after laparoscopic fundoplication
Sign Up to like & getrecommendations! Published in 2019 at "ANZ Journal of Surgery"
DOI: 10.1111/ans.15471
Abstract: Laparoscopic fundoplication is an effective treatment for gastro‐oesophageal reflux disease (GERD). We aimed to assess quality of life (QoL), long‐term residual symptoms, patient satisfaction and use of acid‐suppression medication at 5, 10 and 20 years after… read more here.
Keywords: suppression medication; acid suppression; laparoscopic fundoplication; quality life ... See more keywords
Night-time gastric acid suppression by tegoprazan compared to vonoprazan or esomeprazole.
Sign Up to like & getrecommendations! Published in 2022 at "British journal of clinical pharmacology"
DOI: 10.1111/bcp.15268
Abstract: AIM Nocturnal acid breakthrough has been considered an unmet need of proton pump inhibitors. Tegoprazan, a novel potassium-competitive acid blocker, is expected to show improved properties for this unmet need. This study was aimed to… read more here.
Keywords: night time; night; acid suppression; tegoprazan ... See more keywords
Evolving trends in acid suppression therapy among patients undergoing dual antiplatelet therapy: A Nationwide study in South Korea from 2018 to 2022
Sign Up to like & getrecommendations! Published in 2025 at "British Journal of Clinical Pharmacology"
DOI: 10.1111/bcp.16398
Abstract: We aimed to examine the recent trends in the use of acid suppression therapies, including proton pump inhibitors (PPIs), histamine‐2 receptor antagonists (H2RAs) and potassium‐competitive acid blockers (P‐CABs), in patients undergoing dual antiplatelet therapy (DAPT)… read more here.
Keywords: patients undergoing; therapy; dual antiplatelet; acid suppression ... See more keywords
Is acid suppression associated with the increased length of stay in diabetic ketoacidosis patients? A nationwide analysis
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Internal Medicine"
DOI: 10.1111/joim.13466
Abstract: Diabetic ketoacidosis (DKA) patients present with low serum bicarbonate ( HCO3−${\rm{HCO}}_{3}^{-} $ ), and an increase in its level to ≥15 mEq/L is considered one of the criteria for DKA resolution. Both proton pump inhibitors… read more here.
Keywords: acid suppression; associated increased; diabetic ketoacidosis; increased length ... See more keywords
Infant Reflux in the Primary Care Setting: A Brief Educational Intervention and Management Changes
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DOI: 10.1177/0009922817738339
Abstract: There has been a significant increase in prescription of acid suppression therapy to infants despite limited support for efficacy and safety. Prior studies have shown that educational interventions can improve clinician practices. Our aim is… read more here.
Keywords: intervention; acid suppression; primary care; reflux primary ... See more keywords
Multimodal Intervention Assessing the Appropriateness of Acid Suppression Therapy is Associated With Reduced Prescriptions at the Time of Discharge for Hospitalized Inpatients
Sign Up to like & getrecommendations! Published in 2022 at "Hospital Pharmacy"
DOI: 10.1177/00185787221123212
Abstract: Background: Acid suppression therapy (AST), including proton pump inhibitors and histamine 2 receptor antagonists, are an overused class of medications. When used inappropriately, AST leads to polypharmacy, increased healthcare costs, and possible negative health consequences.… read more here.
Keywords: suppression therapy; acid suppression; ast; intervention ... See more keywords
The Role of Adjuvant Acid Suppression on the Outcomes of Bleeding Esophageal Varices after Endoscopic Variceal Ligation
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DOI: 10.1371/journal.pone.0169884
Abstract: The impact of adjuvant acid suppression via proton pump inhibitors or histamine-2 receptor antagonists after endoscopic variceal ligation remains uncertain. We therefore aimed to evaluate the effect of adjuvant acid suppression on the rebleeding and… read more here.
Keywords: adjuvant acid; acid suppression; variceal ligation; endoscopic variceal ... See more keywords