Early-Life Exposure to Acid-Suppressive Therapy and the Development of Celiac Disease Autoimmunity
Sign Up to like & getrecommendations! Published in 2025 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2025.3376
Abstract: Key Points Question Is acid-suppressive therapy during early life associated with the development of celiac disease? Findings This study included both a cohort design and a test-negative case-control design. Acid-suppressive therapy was associated with celiac… read more here.
Keywords: acid suppressive; early life; celiac disease; suppressive therapy ... See more keywords
Association Between Use of Acid-Suppressive Medications and Antibiotics During Infancy and Allergic Diseases in Early Childhood
Sign Up to like & getrecommendations! Published in 2018 at "JAMA Pediatrics"
DOI: 10.1001/jamapediatrics.2018.0315
Abstract: Importance Allergic diseases are prevalent in childhood. Early exposure to medications that can alter the microbiome, including acid-suppressive medications and antibiotics, may influence the likelihood of allergy. Objective To determine whether there is an association… read more here.
Keywords: suppressive medications; first months; allergic diseases; medications antibiotics ... See more keywords
Acid-suppressive agents and survival outcomes in patients with cancer: a systematic review and meta-analysis
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DOI: 10.1007/s10147-020-01795-7
Abstract: Background Patients with cancer often receive acid-suppressive agents (ASAs) to treat common gastroesophageal reflux and peptic ulcer diseases. Our systematic review addresses the association between ASAs and survival outcomes in these patients. Methods We searched… read more here.
Keywords: survival outcomes; systematic review; patients cancer; acid suppressive ... See more keywords
Pharmacologic Prophylaxis of Stress Ulcer in Non-ICU Patients: A Systematic Review and Network Meta-analysis of Randomized Controlled Trials.
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DOI: 10.1016/j.clinthera.2020.01.008
Abstract: PURPOSE Acid-suppressive medications are widely used in non-intensive care unit (non-ICU) patients for stress ulcer (SU) prophylaxis. However, SU prophylaxis in this population is still controversial. The purpose of this study was to systematically evaluate… read more here.
Keywords: acid suppressive; non icu; meta analysis; icu patients ... See more keywords
Acid Suppressant Use in Pregnancy and Asthma in Offspring: Should We Be Worried?
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DOI: 10.1542/peds.2017-3741
Abstract: * Abbreviations: CI — : confidence interval GERD — : gastroesophageal reflux disease PPI — : proton pump inhibitor Gastroesophageal reflux disease (GERD) is the most common medical complaint in pregnancy, manifesting as heartburn and… read more here.
Keywords: pregnancy; acid suppressant; acid suppressive; asthma offspring ... See more keywords
Effect of acid-suppressive drugs on endoscopic transmural drainage of peripancreatic fluid collections—a randomized controlled trial
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DOI: 10.7717/peerj.19872
Abstract: Background Acid-suppressing drugs affect intestinal microbes by inhibiting the secretion of stomach acid. However, it is not clear whether acid suppressive drugs affect the microorganisms in the peripancreatic effusion and affect the postoperative complications. Methods… read more here.
Keywords: acid suppressive; acid suppressing; suppressive drugs; trial ... See more keywords