Upregulation of Superenhancer‐Driven LncRNA FASRL by USF1 Promotes De Novo Fatty Acid Biosynthesis to Exacerbate Hepatocellular Carcinoma (Adv. Sci. 1/2023)
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Science"
DOI: 10.1002/advs.202204711
Abstract: Superenhancers drive abnormal gene expression in tumors and promote malignancy. However, the relationship between superenhancer‐associated long noncoding RNA (lncRNA) and abnormal metabolism is unknown. This study identifies a novel lncRNA, fatty acid synthesis‐related lncRNA (FASRL),… read more here.
Keywords: hepatocellular carcinoma; acid synthesis; fasrl; lncrna fasrl ... See more keywords
In vitro evaluation of the cariogenic potential of rebaudioside A compared to sucrose and xylitol
Sign Up to like & getrecommendations! Published in 2019 at "Clinical Oral Investigations"
DOI: 10.1007/s00784-019-02908-x
Abstract: Objectives The aim of the present study was to evaluate the growth and acid synthesis of cariogenic pathogens in vitro when rebaudioside A was the sole source of carbon, compared to sucrose, xylitol, and a… read more here.
Keywords: compared sucrose; xylitol; sucrose xylitol; acid synthesis ... See more keywords
Acetic Acid Synthesis from Ethanol: Describing the Synergy Between PdO and m-ZrO2
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DOI: 10.1007/s10562-017-2001-0
Abstract: The PdO and m-ZrO2 oxides show different catalytic properties which are not only complementary but also relevant for the ethanol selective oxidation. Due to the spillover of the oxygenated intermediates from PdO to m-ZrO2 and… read more here.
Keywords: acetic acid; pdo zro2; acid synthesis; ethanol ... See more keywords
Immobilization altering the growth behavior, ammonium uptake and amino acid synthesis of Chlorella vulgaris at different concentrations of carbon and nitrogen.
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DOI: 10.1016/j.biortech.2020.124438
Abstract: Nitrogen recycling by microalgae has aroused considerable attention. In this study, immobilized Chlorellavulgaris with 5-day mixotrophic cultivation to recover ammonium (NH4+-N) were systematically investigated under various sodium acetate (CH3COONa) and ammonium chloride (NH4Cl) concentrations, and… read more here.
Keywords: amino acid; suspended cells; acid synthesis; carbon nitrogen ... See more keywords
Polygonum multiflorum Thunb suppress bile acid synthesis by activating Fxr-Fgf15 signaling in the intestine.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of ethnopharmacology"
DOI: 10.1016/j.jep.2018.12.007
Abstract: ETHNOPHARMACOLOGICAL RELEVANCE Polygonum multiflorum Thunb (Heshouwu, HSW) is commonly used in clinical medicine, while the hepatotoxicities of HSW are reported increasingly in recent years. Currently, researchers have demonstrated an essential role of Bile Acids (BAs)… read more here.
Keywords: polygonum multiflorum; multiflorum thunb; hsw; fxr fgf15 ... See more keywords
Putative functions of EpsK in teichuronic acid synthesis and phosphate starvation in Bacillus licheniformis
Sign Up to like & getrecommendations! Published in 2022 at "Synthetic and Systems Biotechnology"
DOI: 10.1016/j.synbio.2022.04.001
Abstract: Extracellular polymeric substances (EPSs) are extracellular macromolecules in bacteria, which function in cell growth and show potential for mechanism study and biosynthesis application. However, the biosynthesis mechanism of EPS is still not clear. We herein… read more here.
Keywords: phosphate starvation; acid synthesis; synthesis; bacillus licheniformis ... See more keywords
C6-Substituted methanopyrrolidine β-amino acid: synthesis and characterization of oligomeric foldamers
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DOI: 10.1016/j.tetlet.2020.152240
Abstract: Abstract Highly conformation constrained β-proline based methanopyrrolidine-5-carboxylic acids (6, MetPyr-5-acids, or MetPyr-β-amino acids) derivatives were designed, synthesized, and investigated to control peptide conformation and oligomer folding. Enhanced order of folding uniformity correlated with length of… read more here.
Keywords: substituted methanopyrrolidine; amino acid; characterization oligomeric; methanopyrrolidine amino ... See more keywords
Metabolic adaptation to high-starch diet in largemouth bass (Micropterus salmoides) was associated with the restoration of metabolic functions via inflammation, bile acid synthesis and energy metabolism
Sign Up to like & getrecommendations! Published in 2022 at "British Journal of Nutrition"
DOI: 10.1017/s0007114522001180
Abstract: Abstract A short-term 2-week (2w) and long-term 8-week (8w) feeding trial was conducted to investigate the effects of low-starch (LS) and high-starch (HS) diets on the growth performance, metabolism and liver health of largemouth bass… read more here.
Keywords: metabolism; acid synthesis; bile acid; largemouth bass ... See more keywords
Function of the Polyketide Synthase Domains of Schizochytrium sp. on Fatty Acid Synthesis in Yarrowia lipolytica.
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DOI: 10.1021/acs.jafc.2c08383
Abstract: It is well known that polyunsaturated fatty acids (PUFAs) in Schizochytrium sp. are mainly synthesized via the polyketide synthase (PKS) pathway. However, the specific mechanism of PKS in fatty acid synthesis is still unclear. In… read more here.
Keywords: yarrowia lipolytica; acid synthesis; fatty acid; synthase ... See more keywords
Targeting cellular fatty acid synthesis limits T helper and innate lymphoid cell function during intestinal inflammation and infection
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DOI: 10.1038/s41385-020-0285-7
Abstract: CD4 + T cells contribute critically to a protective immune response during intestinal infections, but have also been implicated in the aggravation of intestinal inflammatory pathology. Previous studies suggested that T helper type (Th)1 and… read more here.
Keywords: fatty acid; infection; acid synthesis; function ... See more keywords
Computational and experimental identification of strong synergy of the Fe/ZnO catalyst in promoting acetic acid synthesis from CH4 and CO2.
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DOI: 10.1039/c9cc10055e
Abstract: DFT calculations have identified reaction pathways for acetic acid synthesis from CO2 and CH4 on ZnO, Cu/ZnO and Fe/ZnO surfaces. Fe/ZnO exhibits strong synergy in facilitating CH4 activation, dissociation and C-C coupling. Thus, the surface… read more here.
Keywords: zno; ch4; acid synthesis; strong synergy ... See more keywords