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Published in 2024 at "Clinical and Experimental Medicine"
DOI: 10.1007/s10238-024-01463-4
Abstract: Cancer has emerged as a significant threat to human health. Nucleic acid therapeutics regulate the gene expression process by introducing exogenous nucleic acid fragments, offering new possibilities for tumor remission and even cure. Their mechanism…
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Keywords:
nucleic acid;
cancer;
delivery;
acid therapeutics ... See more keywords
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Published in 2025 at "Cancer Research"
DOI: 10.1158/1538-7445.am2025-483
Abstract: Cancer therapies face the challenge of specificity-limiting toxicity to normal cells and maximizing it in malignant ones. The last two decades have seen significant advancements in therapeutics that increase specificity; however, these remain elusive for…
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Keywords:
nucleic acid;
specificity;
sf3b1 mutant;
acid therapeutics ... See more keywords
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Published in 2024 at "Molecules"
DOI: 10.3390/molecules29194737
Abstract: Nucleic acid therapeutics are promising alternatives to conventional anti-cancer therapy, such as chemotherapy and radiation therapy. While conventional therapies have limitations, such as high side effects, low specificity, and drug resistance, nucleic acid therapeutics work…
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Keywords:
nucleic acid;
anti cancer;
therapy;
acid therapeutics ... See more keywords