Synthesis of Amino Acid α-Thioethers and Late-Stage Incorporation into Peptides.
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DOI: 10.1021/acs.orglett.2c01297
Abstract: The accelerating discovery of structurally distinct peptide natural products bearing α-thioether cross-links, such as the family of sactipeptide natural products, highlights the need for strategies to synthesize this underexplored functional motif. Herein, we describe the… read more here.
Keywords: acid thioethers; late stage; amino acid; synthesis amino ... See more keywords