Pillar[5]arene-based acid-triggered supramolecular porphyrin photosensitizer for combating bacterial infections and biofilm dispersion.
Sign Up to like & getrecommendations! Published in 2021 at "Advanced healthcare materials"
DOI: 10.1002/adhm.202102015
Abstract: The treatment of pathogenic bacterial infection has long been the most serious threat to human life and attracted widespread attention. Herein, we construct a supramolecular photosensitizer platform based on carboxylatopillar[5]arene (CP5) and tetrafluorophenyl porphyrin functionalized… read more here.
Keywords: porphyrin photosensitizer; acid triggered; arene; cp5 ... See more keywords
Acid-triggered degradable diblock poly(doxorubicin)-polyethylene glycol polyprodrug with doxorubicin as structural unit for tumor intracellular delivery.
Sign Up to like & getrecommendations! Published in 2021 at "International journal of pharmaceutics"
DOI: 10.1016/j.ijpharm.2021.121142
Abstract: Polyprodrugs, in which drug was used as the structural unit by linking with each other via the dynamic covalent bonds in the main chain, are expected to endow excellent drug delivery performance. Here, acid-triggered degradable… read more here.
Keywords: structural unit; degradable diblock; triggered degradable; acid triggered ... See more keywords
Acid-Triggered Polymer Backbone Degradation and Disassembly to Achieve Release of Camptothecin from Functional Polyphosphoramidate Nanoparticles
Sign Up to like & getrecommendations! Published in 2018 at "ACS Macro Letters"
DOI: 10.1021/acsmacrolett.8b00377
Abstract: Camptothecin (CPT) is a promising anticancer drug, yet its therapeutic potential has been limited by poor water solubility and facile hydrolysis of the lactone form into an inactive carboxylate form at neutral pH. In this… read more here.
Keywords: triggered polymer; polymer backbone; acid triggered; functional polyphosphoramidate ... See more keywords
Acid-Triggered, Acid-Generating, and Self-Amplifying Degradable Polymers.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.8b07705
Abstract: We describe the 3-iodopropyl acetal moiety as a simple cleavable unit that undergoes acid catalyzed hydrolysis to liberate HI (p Ka ∼ -10) and acrolein stoichiometrically. Integrating this unit into linear and network polymers gives… read more here.
Keywords: generating self; self amplifying; triggered acid; acid generating ... See more keywords
An acid-triggered BODIPY-based photosensitizer for enhanced photodynamic antibacterial efficacy.
Sign Up to like & getrecommendations! Published in 2022 at "Biomaterials science"
DOI: 10.1039/d2bm00780k
Abstract: Photodynamic inactivation of bacteria has emerged as a promising antibacterial strategy due to its high antibacterial activity and low bacterial resistance. Herein, an acid-triggered photodynamic antibacterial nanoplatform (IBPAAs) was constructed by co-assembly of an acid-triggered… read more here.
Keywords: photodynamic antibacterial; enhanced photodynamic; acid triggered; photosensitizer ... See more keywords
Lewis acid-triggered photocatalytic hydrogen peroxide production in an aluminum-based metal-organic framework.
Sign Up to like & getrecommendations! Published in 2022 at "Chemical communications"
DOI: 10.1039/d2cc04454d
Abstract: Al-MIL-101-NH2, which was previously regarded as being inactive as a photocatalyst, produces hydrogen peroxide (H2O2) via O2 reduction under visible-light irradiation, accompanied by efficient suppression of undesired H2O2 decomposition. The low-coordination Lewis acid sites in… read more here.
Keywords: hydrogen peroxide; acid triggered; triggered photocatalytic; lewis acid ... See more keywords
Nucleic acid–triggered tumoral immunity propagates pH‐selective therapeutic antibodies through tumor‐driven epitope spreading
Sign Up to like & getrecommendations! Published in 2022 at "Cancer Science"
DOI: 10.1111/cas.15596
Abstract: Important roles of humoral tumor immunity are often pointed out; however, precise profiles of dominant antigens and developmental mechanisms remain elusive. We systematically investigated the humoral antigens of dominant intratumor immunoglobulin clones found in human… read more here.
Keywords: immunity propagates; acid triggered; immunity; triggered tumoral ... See more keywords