Analysis of single amino acid variations in singlet hot spots of protein‐protein interfaces
Sign Up to like & getrecommendations! Published in 2018 at "Bioinformatics"
DOI: 10.1093/bioinformatics/bty569
Abstract: Motivation Single amino acid variations (SAVs) in protein‐protein interaction (PPI) sites play critical roles in diseases. PPI sites (interfaces) have a small subset of residues called hot spots that contribute significantly to the binding energy,… read more here.
Keywords: amino acid; acid variations; protein protein; singlet hot ... See more keywords
Investigating the Effects of Amino Acid Variations in Human Menin
Sign Up to like & getrecommendations! Published in 2022 at "Molecules"
DOI: 10.3390/molecules27051747
Abstract: Human menin is a nuclear protein that participates in many cellular processes, as transcriptional regulation, DNA damage repair, cell signaling, cell division, proliferation, and migration, by interacting with many other proteins. Mutations of the gene… read more here.
Keywords: effects amino; amino acid; human menin; investigating effects ... See more keywords