Acidic patch histone mutations and their effects on nucleosome remodeling.
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DOI: 10.1042/bst20210773
Abstract: Structural and biochemical studies have identified a histone surface on each side of the nucleosome disk termed 'the nucleosome acidic patch' that acts as a regulatory hub for the function of numerous nuclear proteins, including… read more here.
Keywords: nucleosome remodeling; patch histone; histone mutations; acidic patch ... See more keywords
Multivalent DNA and nucleosome acidic patch interactions specify VRK1 mitotic localization and activity
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DOI: 10.1093/nar/gkac198
Abstract: Abstract A key role of chromatin kinases is to phosphorylate histone tails during mitosis to spatiotemporally regulate cell division. Vaccinia-related kinase 1 (VRK1) is a serine–threonine kinase that phosphorylates histone H3 threonine 3 (H3T3) along… read more here.
Keywords: multivalent dna; patch interactions; nucleosome acidic; dna nucleosome ... See more keywords