Activity of acute pancreatitis is modified by secreted protein acidic and rich in cysteine ablation
Sign Up to like & getrecommendations! Published in 2022 at "United European Gastroenterology Journal"
DOI: 10.1002/ueg2.12262
Abstract: Abstract Background Acute pancreatitis (AP) is a frequent cause for hospitalization. However, molecular determinants that modulate severity of experimental pancreatitis are only partially understood. Objective To investigate the role of secreted protein acidic and rich… read more here.
Keywords: rich cysteine; secreted protein; protein acidic; pancreatitis ... See more keywords
Secreted protein acidic and rich in cysteine (SPARC) regulates thermogenesis in white and brown adipocytes
Sign Up to like & getrecommendations! Published in 2020 at "Molecular and Cellular Endocrinology"
DOI: 10.1016/j.mce.2020.110757
Abstract: SPARC, also known as osteonectin, is well known for its physiological roles in bone formation and tissue remodeling, as well as in cancer pathology; however, evidence regarding its function in adipocytes is lacking. The present… read more here.
Keywords: protein acidic; sparc; acidic rich; white brown ... See more keywords
Hypertrophic Ligamentum Flavum in Lumbar Spine Stenosis Is Associated With the Increased Expression of Secreted Protein Acidic and Rich in Cysteine.
Sign Up to like & getrecommendations! Published in 2022 at "Global spine journal"
DOI: 10.1177/21925682221138766
Abstract: STUDY DESIGN Basic research. OBJECTIVES Secreted protein acidic and rich in cysteine (SPARC) is a critical pro-fibrotic mediator. This study aims to characterize the role of SPARC in hypertrophic ligamentum flavum (LF) and fibrosis. METHODS… read more here.
Keywords: secreted protein; rich cysteine; expression; protein acidic ... See more keywords
Secreted Protein Acidic and Rich in Cysteine Mediates the Development and Progression of Diabetic Retinopathy
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DOI: 10.3389/fendo.2022.869519
Abstract: Backgrounds Diabetic retinopathy (DR) is one of the most severe microvascular complications of diabetes mellitus (DM). Secreted protein acidic and rich in cysteine (SPARC) has been found to play an important role in many diseases,… read more here.
Keywords: role; secreted protein; protein acidic; diabetic retinopathy ... See more keywords
Secreted Protein Acidic and Rich in Cysteine as A Regeneration Factor: Beyond the Tissue Repair
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DOI: 10.3390/life11010038
Abstract: Diverse pathologies (inflammation, tissues injuries, cancer, etc.) and physiological conditions (obesity, physical activity, etc.) induce the expression/secretion of the matricellular protein, secrete protein acidic and rich in cysteine (SPARC). SPARC contributes to the creation of… read more here.
Keywords: protein acidic; acidic rich; regeneration; tissue ... See more keywords