Synergistic size and charge conversions of functionalized PAMAM dendrimers under the acidic tumor microenvironment.
Sign Up to like & getrecommendations! Published in 2022 at "Biomaterials science"
DOI: 10.1039/d2bm00643j
Abstract: Developing nanomedicine with highly adaptive behaviors has shown great effectiveness in cancer treatment. However, the multi-functional integration of nano-therapeutic systems inevitably leads to complexity in the structure and impairs the operational efficiency or performance. Herein,… read more here.
Keywords: acidic tumor; tumor; tumor microenvironment; size charge ... See more keywords
The acidic tumor microenvironment: a target for smart cancer nano-theranostics
Sign Up to like & getrecommendations! Published in 2018 at "National Science Review"
DOI: 10.1093/nsr/nwx062
Abstract: The acidic tumor microenvironment (TME), which mainly results from the high glycolytic rate of tumor cells, has been characterized as a hallmark of solid tumors and found to be a pivotal factor participating in tumor… read more here.
Keywords: acidic tumor; acidic tme; target; tme ... See more keywords