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Glutamate-Induced Deregulation of Krebs Cycle in Mitochondrial Encephalopathy Lactic Acidosis Syndrome Stroke-Like Episodes (MELAS) Syndrome Is Alleviated by Ketone Body Exposure

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Published in 2022 at "Biomedicines"

DOI: 10.3390/biomedicines10071665

Abstract: (1) Background: The development of mitochondrial medicine has been severely impeded by a lack of effective therapies. (2) Methods: To better understand Mitochondrial Encephalopathy Lactic Acidosis Syndrome Stroke-like episodes (MELAS) syndrome, neuronal cybrid cells carrying… read more here.

Keywords: lactic acidosis; cycle; glutamate; encephalopathy lactic ... See more keywords