2‐Carboxyquinoline Boronic Acids as Highly Potent KPC Inhibitors
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DOI: 10.1002/cmdc.202400901
Abstract: The expression of Klebsiella pneumoniae carbapenemase (KPC), a type of carbapenem‐hydrolyzing β‐lactamase, in Gram‐negative bacteria has caused significant bacterial resistance to carbapenems, the antibiotic of last resort. Herein, we describe the discovery of 2‐carboxyquinoline boronic… read more here.
Keywords: potent kpc; highly potent; carboxyquinoline boronic; acids highly ... See more keywords