Copper-Catalyzed One-Pot Synthesis of 2,5-Disubstituted 1,3,4-Oxadiazoles from Arylacetic Acids and Hydrazides via Dual Oxidation
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DOI: 10.1021/acsomega.2c01586
Abstract: A simple and efficient protocol has been developed to access symmetrical and unsymmetrical 2,5-disubstituted 1,3,4-oxadiazoles from arylacetic acids and hydrazides via copper-catalyzed dual oxidation under an oxygen atmosphere. Oxidative decarboxylation of arylacetic acids and oxidative… read more here.
Keywords: acids hydrazides; oxadiazoles arylacetic; dual oxidation; disubstituted oxadiazoles ... See more keywords