Nucleic Acids as a Nature‐Inspired Scaffold for Macromolecular Prodrugs of Nucleoside Analogues
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DOI: 10.1002/advs.201802095
Abstract: Abstract Macromolecular prodrugs (MP) built on the natural phosphodiester and deoxyribose backbone are developed using marketed antiviral nucleoside analogues. These MP are synthesized using automated synthesis, have defined molecular composition, and have a natural mechanism… read more here.
Keywords: acids nature; nucleic acids; nature inspired; nucleoside analogues ... See more keywords
N-Alkyl-α-amino acids in Nature and their biocatalytic preparation.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of biotechnology"
DOI: 10.1016/j.jbiotec.2019.01.006
Abstract: N-Alkylated-α-amino acids are useful building blocks for the pharmaceutical and fine chemical industries. Enantioselective methods of N-alkylated-α-amino acid synthesis are therefore highly valuable and widely investigated. While there are a variety of chemical methods for… read more here.
Keywords: nature biocatalytic; acids nature; amino acids; alkylated amino ... See more keywords