N‐methylation in amino acids and peptides: Scope and limitations
Sign Up to like & getrecommendations! Published in 2018 at "Biopolymers"
DOI: 10.1002/bip.23110
Abstract: Active pharmaceutical ingredients (APIs) can be divided into two types, namely chemical and biological entities. Traditionally, the former has been associated with the so‐called small molecules. The revival of peptides in pharmaceutical industry results from… read more here.
Keywords: peptide; amino acids; methylation amino; acids peptides ... See more keywords
Separation and identification of the dl-forms of short-chain peptides using a new chiral resolution labeling reagent
Sign Up to like & getrecommendations! Published in 2022 at "Analytical and Bioanalytical Chemistry"
DOI: 10.1007/s00216-022-04048-w
Abstract: There are several reports of d-amino acids being the causative molecules of serious diseases, resulting in the formation of, for example, prion protein and amyloid β. d-Amino acids in peptides and proteins are typically identified… read more here.
Keywords: hydrolysis; separation identification; amino acids; acids peptides ... See more keywords
Modeling solubility of amino acids and peptides in water and in water+2-propanol mixtures: PC-SAFT vs. gE models
Sign Up to like & getrecommendations! Published in 2021 at "Fluid Phase Equilibria"
DOI: 10.1016/j.fluid.2021.113087
Abstract: Abstract Amino acids and peptides are essential components for many industrial branches. Knowledge on the solubility behavior is required in purification processes, which often involve crystallization as main unit operation. Since the determination of experimental… read more here.
Keywords: water; amino acids; solubility; acids peptides ... See more keywords
Effect of glycation degree on the structure and digestion properties of ovalbumin: A study of amino acids and peptides release after in vitro gastrointestinal simulated digestion.
Sign Up to like & getrecommendations! Published in 2021 at "Food chemistry"
DOI: 10.1016/j.foodchem.2021.131331
Abstract: Glycation can improve the functional properties of protein. However, in vitro and animal studies have shown that glycation induced lysine blockage and impaired protein digestibility. This study aimed to explore the effects of different glycation… read more here.
Keywords: amino acids; glycation; digestion; acids peptides ... See more keywords
Ribosomal incorporation of cyclic β-amino acids into peptides using in vitro translation.
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DOI: 10.1039/d0cc02121k
Abstract: We demonstrate in vitro incorporation of cyclic β-amino acids into peptides by the ribosome through genetic code reprogramming. Further, we show that incorporation efficiency can be increased through the addition of elongation factor P. read more here.
Keywords: incorporation cyclic; amino acids; cyclic amino; acids peptides ... See more keywords
Recent advances in the synthesis of fluorinated amino acids and peptides.
Sign Up to like & getrecommendations! Published in 2023 at "Chemical communications"
DOI: 10.1039/d2cc06787k
Abstract: The site-selective modification of amino acids, peptides, and proteins has always been an intensive topic in organic synthesis, medicinal chemistry, and chemical biology due to the vital role of amino acids in life. Among the… read more here.
Keywords: amino acids; chemistry; synthesis; acids peptides ... See more keywords
Up- or Downregulation of Melanin Synthesis Using Amino Acids, Peptides, and Their Analogs
Sign Up to like & getrecommendations! Published in 2020 at "Biomedicines"
DOI: 10.3390/biomedicines8090322
Abstract: Harmonious synthesis and distribution of melanin in the skin contribute to the expression of beauty and the maintenance of health. When skin pigmentary disorders occur because of internal or external factors or, when there is… read more here.
Keywords: amino acids; melanin; melanin synthesis; acids peptides ... See more keywords
N-Lipidated Amino Acids and Peptides Immobilized on Cellulose Able to Split Amide Bonds
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DOI: 10.3390/ma12040578
Abstract: N-lipidated short peptides and amino acids immobilized on the cellulose were used as catalysts cleaved amide bonds under biomimetic conditions. In order to select catalytically most active derivatives a library of 156 N-lipidated amino acids,… read more here.
Keywords: immobilized cellulose; amino acids; acids peptides; peptides immobilized ... See more keywords
New Fmoc-Amino Acids/Peptides-Based Supramolecular Gels Obtained through Co-Assembly Process: Preparation and Characterization
Sign Up to like & getrecommendations! Published in 2022 at "Polymers"
DOI: 10.3390/polym14163354
Abstract: One of the methods of obtaining supramolecular gels consists of the possibility of self-assembly of low molecular weight gelators (LMWGs). However, LMWG-based gels are often difficult to handle, easy to destroy and have poor rheological… read more here.
Keywords: amino acids; fmoc; acids peptides; new fmoc ... See more keywords